Full Description
The complete immunotherapy reference from basic science to clinical application
Immunotherapy has transformed treatment approaches for cancer, autoimmune diseases, and infectious conditions, yet no single resource has unified its foundational immunology with advanced clinical applications. Frazer's Foundations of Immunotherapy addresses this absence, offering comprehensive coverage co-edited by Fernando Guimaraes, a leading immunotherapy expert and Ian Frazer, co-developer of the HPV vaccine Gardasil. With coverage of CAR T-cell therapy, NK cell therapies, precision immunotherapy, and the microbiome's role in treatment response, this text integrates evolving research with practical protocols for students, researchers, and clinicians.
Readers will also find:
Structured progression from basic immunology principles through cutting-edge therapeutic developments, bridging theory with clinical and research applications
Coverage spanning cancer, autoimmune conditions, and infectious diseases rather than limiting scope to oncology immunotherapy approaches alone
Practical protocols and clinical case studies demonstrating real-world application of immunotherapy principles across diverse patient populations
Expert contributions from leading researchers from globally renowned research groups and institutions, ensuring authoritative, current content
Extensive illustrations simplifying complex immunological concepts for advanced students, clinical trainees, and practicing professionals alike
This guide will benefit advanced students in biomedical and medical programs, immunology and oncology professionals, biotechnology researchers, and clinical trainees. Frazer's Foundations of Immunotherapy provides the structured pathway from fundamental principles to therapeutic applications that this rapidly evolving field demands.
Contents
PART I: Foundations of Immunotherapy
Chapter 1: History and Development of Immunotherapies - Key breakthroughs and milestones, from early immunology to contemporary immunotherapy.
Chapter 2: Introduction to Immunology and Immune Modulation
Chapter 3: Mechanisms of Immune Evasion and Immune Surveillance: Cellular Barriers to Immunotherapy
Part II: Immunotherapy in Cancer
Chapter 4: Cancer Immunotherapy: Key Concepts and Techniques
Chapter 5: Immune Checkpoint Inhibitors in Cancer: Mechanisms, Clinical Use, and Challenges
Chapter 6: Advancements in CAR T and CAR NK cell therapies
Chapter 7: Therapeutic cancer vaccines: challenges and successes in cancer immunotherapy.
Part III: Immunotherapy in Infectious Diseases
Chapter 8: Immunotherapy for Viral Infections: Mechanisms, Clinical Applications, and Future Directions
Chapter 9: Immunotherapy for Microbial Infections: Addressing Bacterial Resistance and Parasitic Infections with Immunotherapy
Chapter 10: Vaccine Development and Immune Response Optimization
Part IV: Immunotherapy in Transplantation Settings, Autoimmune and Inflammatory Diseases
Chapter 11: Engineering regulatory T cells: applications for autoimmune disorders
Chapter 12: Immunotherapy in Transplantation Settings.
Chapter 13: Immunotherapy for the global prevention of haemolytic disease of the foetus and newborn
Chapter 14: Advances in Engineered Immune Cells - Latest advancements in CRISPR, CAR-T, and other immune cell engineering techniques.
Part V: Advanced Immunotherapy Techniques and Applications
Chapter 15: Personalized Immunotherapy and Biomarker-Driven Approaches
Chapter 16: Immunotherapy and the Microbiota: Exploring microbiota-immune interactions and their impact on immunotherapy efficacy.
Chapter 17: Veterinary immunotherapy
Chapter 18: Emerging Immunotherapies and Future Horizons
