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Full Description
Innovative title providing a systematic account of new predictive alignment-free methods in genomics and bioinformatics, emphasizing their computational efficiency
Predictive Methods for Genomics and Evolution provides a cohesive overview of major alignment-based and alignment-free methods in genomics and bioinformatics, primarily based on DNA/RNA. Throughout the book, contrasts between current conventional methods and novel alignment-free methods are presented and evaluated across a wide range of topics.
Written by a team of experienced academics with significant research experience in the field, Predictive Methods for Genomics and Evolution discusses sample topics including:
Major unresolved problems in biology including the most fundamental concept of species, the nature of evolution and speciation, phylogenetic inference, pathogenicity, and the origin of life
Limitations of alignment-based predictive technologies such as high resource usage
Novel interpretations of current hypotheses from a biological perspective with wide-ranging applications in bioinformatics and medicine
Insights on the shift in the research status quo towards a wider application of alignment-free methodologies, fueled by increased availability of data and advances in science and technology
Predictive Methods for Genomics and Evolution is an essential guide on the subject for professionals, academics, researchers, and students within the fields of genomics, evolutionary biology, phylogenetics and taxonomy, and computational biology and bioinformatics, as well as medical practitioners in related fields.
Contents
Contents
Chapter 1 What is Biology?
Chapter 2 Genomes to Phenotypes, Environments, and Genomes
Chapter 3 Species Definitions and their Limitations
Chapter 4 Speciation and Evolution
Chapter 5 From Genomes to Evolution
Chapter 6 Conventional Phylogenetics and Systematics
Chapter 7 New Approaches to Phylogenetics
Chapter 8 About the Origin of Life
Chapter 9 Towards an Analytical Biology
Chapter 10 Appendices