Full Description
Comprehensive reference to pathology in small laboratory mammals with an emphasis on pathogenesis and diagnostic features of diseases
The Fifth Edition of Pathology of Laboratory Rodents and Rabbits offers a thorough update to this comprehensive reference of diseases in mice, rats, hamsters, gerbils, guinea pigs, chinchillas, and rabbits. Emphasizing explanations of pathogenesis and diagnostically relevant features of diseases, the book is logically organized by species and richly illustrated with 690 color photographs and photomicrographs to show the features of common or classic diseases.
This edition adds a new chapter on chinchillas and new information on immunodeficient and humanized mice, as well as updates throughout to reflect new information and changes in the field. The content has been expanded to include diseases and disorders of feral, wild, companion, and livestock counterparts of laboratory rodents and rabbits, including zoonotic diseases.
Topics discussed in Pathology of Laboratory Rodents and Rabbits for each species include:
Anatomic and physiologic features
DNA and RNA viral infections
Bacterial, fungal, and parasitic infections
Nutritional, metabolic, and toxic disorders
Non-neoplastic organ system disorders
Neoplasms
Pathology of Laboratory Rodents and Rabbits is an essential reference for laboratory animal veterinarians and veterinary anatomic pathologists, as well as clinicians seeing small exotic mammals.
Contents
Previous Edition Authors vii
Preface ix
Acknowledgments xi
1 Mouse 1
Introduction 1
Anatomic Features 5
Bibliography for Introduction and Anatomic Features 11
Infections of Laboratory Mice 13
DNA Viral Infections 14
RNA Viral Infections 26
Bibliography for Viral Infections 49
Bacterial Infections 58
Bibliography for Bacterial Infections 84
Fungal Infections 93
Bibliography for Fungal Infections 95
Parasite Infections 96
Bibliography for Parasite Infections 103
Metabolic and Toxic Disorders 105
Bibliography for Metabolic and Toxic Disorders 109
Non-neoplastic Organ System Disorders 110
Bibliography for Non-neoplastic Organ System Disorders 127
Neoplasms 132
Bibliography for Neoplasms 142
Xenotransplantation in Globally Immunodeficient NOD Mice 144
Bibliography for Xenotransplantation in Globally Immunodeficient NOD Mice 150
2 Rat 152
Introduction 152
Anatomic Features 152
Bibliography for Introduction and Anatomic Features 155
DNA Viral Infections 155
RNA Viral Infections 159
Bibliography for Viral Infections 166
Bacterial Infections 170
Bibliography for Bacterial Infections 183
Fungal Infections 188
Bibliography for Fungal Infections 191
Parasite Infections 192
Bibliography for Parasite Infections 198
Nutritional, Metabolic, and Toxic Disorders 200
Bibliography for Nutritional, Metabolic, and Toxic Disorders 201
Non-neoplastic Organ System Disorders 202
Bibliography for Non-neoplastic Organ System Disorders 214
Neoplasia 217
Bibliography for Neoplasms 225
3 Hamster 227
Introduction 227
Anatomic Features 227
Behavioral Features 228
Bibliography for Introduction, Anatomic, and Behavioral Features 229
DNA Viral Infections 229
RNA Viral Infections 233
Bibliography for Viral Infections 234
Bacterial Infections 236
Fungal Infections 243
Bibliography for Bacterial and Fungal Infections 243
Parasite Infections 246
Bibliography for Parasite Infections 250
Nutritional and Metabolic Disorders 251
Bibliography for Nutritional and Metabolic Disorders 253
Non-neoplastic Organ System Disorders 254
Bibliography for Non-neoplastic Organ System Disorders 257
Neoplasms 258
Bibliography for Neoplasms 259
4 Gerbil 261
Introduction 261
Anatomic Features 261
Bibliography for Introduction and Anatomic Features 262
Viral Infections 263
Bibliography for Viral Infections 263
Bacterial Infections 263
Fungal Infections 266
Bibliography for Bacterial and Fungal Infections 266
Parasite Infections 268
Bibliography for Parasite Infections 269
Nutritional, Metabolic, and Toxic Disorders 269
Bibliography for Nutritional, Metabolic, and Toxic Disorders 271
Non-neoplastic Organ System Disorders 271
Respiratory System Disorders 272
Bibliography for Non-neoplastic Organ System Disorders 273
Neoplasms 274
Bibliography for Neoplasms 275
5 Guinea Pig 277
Introduction 277
Behavioral, Physiologic, and Anatomic Features 277
Bibliography for Introduction, Behavioral, Physiologic, and Anatomic Features 283
DNA Viral Infections 284
RNA Viral Infections 286
Bibliography for Viral Infections 287
Bacterial Infections 289
Bibliography for Bacterial Infections 300
Fungal Infections 304
Bibliography for Fungal Infections 305
Parasite Infections 306
Bibliography for Parasite Infections 311
Genetic Disorders 312
Nutritional, Metabolic, and Toxic Disorders 313
Bibliography for Genetic, Nutritional, Metabolic, and Toxic Disorders 318
Non-neoplastic Organ System Disorders 320
Bibliography for Non-neoplastic Organ System Disorders 329
Neoplasms 331
Bibliography for Neoplasms 333
6 Chinchilla 335
Introduction 335
Behavioral, Physiologic, and Anatomic Features 335
General References 337
Bibliography for Behavioral, Physiologic, and Anatomic Features 337
Viral Infections 337
Bibliography for Viral Infections 338
Bacterial Infections 338
Bibliography for Bacterial Infections 344
Fungal Infections 345
Bibliography for Fungal Infections 346
Parasite Infections 347
Bibliography for Parasite Infections 349
Nutritional, Metabolic, and Toxic Disorders 350
Bibliography for Nutritional, Metabolic, and Toxic Disorders 350
Non-neoplastic Organ System Disorders 351
Musculoskeletal System Disorders 354
Urinary System Disorders 354
Female Reproductive System Disorders 354
Male Reproductive System Disorders 355
Bibliography for Non-neoplastic Organ System Disorders 355
Neoplasms 355
Bibliography for Neoplasms 356
7 Rabbit 357
Introduction 357
Behavioral, Physiologic, and Anatomic Features 357
Bibliography for Introduction, Behavioral, Physiologic, and Anatomic Features 361
DNA Viral Infections 362
RNA Viral Infections 370
Bibliography for Viral Infections 375
Bacterial Infections 379
Bibliography for Bacterial Infections 402
Fungal Infections 409
Bibliography for Fungal Infections 415
Parasite Infections 417
Bibliography for Parasite Infections 429
Genetic Disorders 432
Bibliography for Genetic Disorders 435
Nutritional, Metabolic, and Toxic Disorders 436
Bibliography for Nutritional, Metabolic, and Toxic Disorders 443
Non-neoplastic Organ System Disorders 445
Bibliography for Non-neoplastic Organ System Disorders 454
Neoplasms 457
Bibliography for Neoplasms 461
Index 463
