Full Description
Elastic Fiber Matrices: Biomimetic Approaches to Regeneration and Repair provides a comprehensive resource on the intrinsic and pathological aberrations of the complex process of elastic matrix assembly and/or variations thereof in different elastic tissue types, and on strategies to regenerate or restore lost elastin matrix, either in vitro or in vivo, including biomimetic elastin-like-peptides, gene therapy, drug delivery, tissue engineering (biomolecules, scaffolds, and mechanical stimuli), pharmacological approaches, elastin stabilization and preservation, stem cell therapy, allografts/xenografts, and synthetic/biological elastomers.
Comprised of individual chapters contributed by leading researchers and scientists in the field, the text details current approaches for elastin matrix regeneration and repair, identifying their various advantages and limitations while offering valuable insight into emerging trends. Thus, this book is a must-have guide for academicians and industry professionals working in the areas of connective tissue biology, tissue engineering, dermal and cardiovascular biomaterials, and drug delivery.
Contents
Assembly and Properties of Elastic Fibers. Pathology of the Elastic Matrix. Synthetic-Elastin Systems. Biomolecular Regulation of Elastic Matrix Regeneration and Repair. Scaffold and Biomechanical Transductive Approaches to Elastic Tissue Engineering. Pharmacologic Strategies for Preserving Elastic Matrix. Sourcing and Manipulating Stem Cells for Elastin Regeneration Applications. Regulating Elastogenesis Using Proteoglycans. Recent Approaches and Future Perspectives on Elastin Regeneration and Repair.
