Full Description
Most people who develop dementia will never be diagnosed, and therefore lack access to treatment and care from specialists in the field. This new edition provides updated guidance on how behavioral symptom reflect the changes occurring in the brain, and how these can help generalist clinicians to accurately diagnose neurodegenerative diseases. This practical book is aimed at healthcare professionals working in neurology, psychiatry and neuropsychology wanting to enhance the skills and knowledge needed to successfully manage these diseases. Simple approaches to bedside mental status testing, differential diagnosis and treatment, and interpreting neuropsychological testing and neuroimaging findings are covered. Introductory chapters outline dementia epidemiology and dementia neuropathology whilst chapters new to this edition describe the improvements in diagnostic capabilities in recent years, including blood based and cerebrospinal biomarkers and emerging biologically based therapies. Chapters on sleep disorders, and chronic traumatic encephalopathy and traumatic brain injury have also been expanded.
Contents
Part I. Introductory Chapters on Dementia: 1. Dementia at the bedside Bradley F. Boeve and Bruce L. Miller; 2. Brief cognitive assessment Elena Tsoy, Katherine Possin; 3. Neuropsychiatric symptoms of dementia Yavuz Ayhan, Bruce L Miller; 4. Neuropathology of dementia Eun-Joo Kim, Sarat Vatsavayai and William W. Seeley; 5. Neurotransmitters and neuromodulators in dementia Neus Falgàs Martínez, Caroline Lew, Alejandra Sánchez López, Cathrine Petersen and Lea T. Grinberg; 6. Cerebrospinal fluid, molecular neuroimaging, and blood biomarkers of neurodegenerative disease: past, present, and future David N. Soleimani-Meigoon and Gil D. Rabinovici; 7. Magnetic resonance imaging in dementia Chloe Anastassiadis, Howard Rosen and Maria Carmela Tartaglia; 8. Epidemiology and risk-factors for dementia Christina S. Dintinca and Kristine Yaffe; 9. Genetic approaches to neurodegenerative disease Leonel T. Takada and Jennifer Yokoyama; Part II. The Dementias: 10. Alzheimer's disease: preclinical to advanced dementia Neus Falgas Martinez and Raquel Sánchez del Valle Díaz; 11. The behavioral variant of frontotemporal dementia: preclinical to advanced dementia Ignacio Illan-Gala and Bruce L. Miller; 12. Early features of primary progressive aphasia Zachary A. Miller, Gaia C. Santi and Maria Luisa Gorno Tempini; 13. The Cognitive neurology of corticobasal degeneration and progressive supranuclear palsy Suzee E. Lee and Carolyn Fredericks; 14. Mild cognitive impairment across the dementias Ronald C. Peterson; 15. Cognitive disorders of the very old: from clinic to pathology Victor Valcour and Lea T. Grinberg; 16. Posterior cortical atrophy Zeinab Abdi, Emma Harding, Victoria Pelak, Keir X. X. Yong and Sebastian J Crutch; 17. Cognitive and behavioral abnormalities of vascular cognitive impairment Hyemin Jang, Jee Hyang Jeong, Eun-Joo Kim, Duk L. Na and Sang Won Seo; 18. Creutzfeldt-Jakob disease and other prion diseases Igor Prufer Araujo and Michael D. Geschwind; 19. Chronic traumatic encephalopathy Breton M. Asken, David C. Perry and Raquel C. Gardner; 20. Normal pressure hydrocephalus Neill R. Graff-Radford and Benjamin D. Elder; Part iii. Treatment of the Dementias: 21. Treatment of alzheimer's disease Jeffrey L. Cummings; 22. Treatment of frontotemporal dementia Doris Chen, Lawren VandeVrede and Adam L. Boxer; 23. Treatment of dementia with lewy body Bradley F. Boeve; 24. Delirium masquerading as dementia Sara C. LaHue and S. Andrew Josephson; 25. Sleep issues in dementia Sandra Giménez and Bradley F. Boeve; 26. Caregiving in dementia Jennifer Merrilees, Sarah Dulaney and Robert W. Levenson; 27. Legal Issues in dementia Jalayne Arias, Megan Wright and Ana Tylor.
