Genetics, Trauma, and the Brain : The Fragile Thread

di Santo, Patrick

Cambridge Scholars Publishing（2026/08発売）

• 製本 Hardcover:ハードカバー版／ページ数 352 p.
• 言語 ENG
• 商品コード 9781036475741

Full Description

This groundbreaking volume investigates the subtle and often overlooked connections between genetic variation, trauma, and brain development. Drawing on clinical case studies, chromosomal microarray findings, and gene-environment models, the authors explore how neurodevelopmental outcomes are shaped by early-life stressors—including even mild traumatic brain injury—and how these exposures can alter emotional, cognitive, and academic trajectories across the lifespan.Accessible to both practitioners and general readers, the book introduces key mechanisms such as FGGY-PTEN (phosphatase and tensin homolog) signaling and absence of heterozygosity, while also highlighting the social and structural factors that intensify vulnerability. A regional focus on underserved and rural populations underscores the need for early detection and targeted care.Designed for clinicians, educators, genetic counselors, and public health advocates, this book builds a vital bridge between molecular insight and practical intervention, arguing that prevention and precision care must begin far earlier than current systems allow.