Full Description
This edition, like the previous editions of this successful text, tries to summarize the controversies and discuss the scientific basis for various causes of Recurrent Pregnancy Loss in depth and to clarify the various treatment modalities. Much of the controversy that previously seemed to have been settled in many areas of recurrent pregnancy loss has now returned again, particularly regarding the use of progestogens, PGT-A, Filgrastim and anticoagulants, giving this new edition new relevance. Also included here are the continuing advances in genetics and immunomodulation; and the text includes discussion of the roles of evidence-based medicine and personalized medicine and the treatment of the resistant patient.
Both general gynaecologists and specialists in recurrent pregnancy loss will find this a helpful reference for their approach to patients.
FROM REVIEWS OF PREVIOUS EDITIONS
"a leading team ... successfully reviews the controversies surrounding each topic... Essential reading for any physician counseling or treating women with recurrent pregnancy loss" (European Gynecology & Obstetrics)
"needed, logically organized, and balanced... a welcome reference" (Fertility & Sterility)
Contents
1.The Epidemiology of Recurrent Pregnancy Loss- Ole B. Christiansen 2.The signaling between embryo and mother as a basis for the development of tolerance Eytan R. Barnea 3.Recurrent Pregnancy Loss: From Evidence Based to Personalised Medicine- Howard J.A Carp 4. Collection of Data and Role of Artificial Intelligence- Abraham Tsur and Oren Barak 5.The genetics of Recurrent Pregnancy Loss- Anat Grossman-Jonish 6.Epigenetic Regulation in RPL - Howard Carp and Dov Feldberg 7.The Endometrial factor in Recurrent Pregnancy Loss - Ka Ying Bonnie Ng and Ying Cheong 8.Fetal Structural Malformations and Recurrent Pregnancy Loss- Howard J.A. Carp, Thomas Philipp, Micha Baum, and Michal Berkenstadt 9.The endocrinology of Recurrent Pregnancy Loss- Pluchino Nicola, Hounga Ayadjenou, and Andrea Riccardo Genazzani 10.The etiology of the Antiphospholipid syndrome - Cristina Garufi, Giuliana Beneduce,Francesca Rizzo, Ester Garufi, Yehuda Shoenfeld, and Sara De Carolis 11.Defects in coagulation factors leading to recurrent pregnancy loss- Aida Inbal and Howard Carp 12.The immunobiology of recurrent miscarriage- Marighoula Varla-Leftherioti, Theodora Keramitsoglou, Barbara Geladakis, and Christina Tsekoura 13. Uterine anomalies and recurrent pregnancy loss- Roy Mashiach, Daniel S. Seidman, and Mordechai Goldenberg 14.The Male Factor in Recurrent Pregnancy Loss- Catherine F. Ingram, Nannan Thirumavalavan, Marc Goldstein, and Dolores J. Lamb 15. Infection and the microbiome leading to pregnancy loss- Mayumi Sugiura-Ogasawara, Hiroyuki Yoshihara, Shinobu Goto, and Tamao Kitaori 16.Inflammatory Placental Disorders and RPL-Keren Ofir and Denise Dana Frank 17.Ultrasound follow up in Early Pregnancy- Akhila Vasudeva and Pratap Kumar 18.Biochemical Pregnancies- Howard. J. A. Carp and Daniel S. Seidman 19.Threatened miscarriage and Recurrent Pregnancy Loss- Howard J. A. Carp 20. The Role of Cerclage and Pessaries - Abraham Tsur, Howard J. A. Carp, and Israel Hendler 21.What genetic screening is appropriate in Recurrent Pregnancy Loss?- Peter Benn and Howard J. A.Carp 22. Obstetric Outcomes after Recurrent Pregnancy Loss - Rakefet Yoeli Ulman, Howard J.A. Carp, Shali Mazaki-Tovi 23.Investigation protocol for recurrent pregnancy loss-Howard J.A. Carp 24. Should Progestogen supplementation be used in Recurrent Pregnancy Loss? Yes- Pedro Melo and Arri Coomarasamy 25.Should Progestogen supplementation be used in Recurrent Pregnancy Loss? No - Abdullatif Elfituri, Stergios K Doumouchtsis, Mudiaga Eseajeberuo Zini, Ramesh Ganapathy, and Hassan Shehata 26.hCG supplementation in Recurrent Pregnancy Loss- Carlo Ticconi and C.V. Rao 27.Antiphospholipid Syndrome: Management of the Obstetric Patient- Ashley E. Benson and D. Ware Branch 28.Can Recurrent Pregnancy Loss Be Prevented by Empirical AntithromboticAgents? Yes- Michael Kupferminc 29. Can Recurrent Pregnancy Loss Be Prevented by Empirical Antithrombotic Agents? No- Pelle Lindqvist 30.Empirical In Vitro Fertilization for Recurrent Pregnancy Loss: Is it a valid concept? - Michal Kirshenbaum and Raoul Orvieto 31. Should PGT-A be performed in Recurrent Pregnancy Loss? Yes- Karissa C Hammer and Ilan Tur-Kaspa 32. Debate: Should PGT-A be performed in Recurrent Pregnancy Loss? No- Raoul Orvieto and Norbert Gleicher 33.Third Party Reproduction in Recurrent Pregnancy Loss- Gautam Nand Allahbadia, Akanksha Allahbadia, and Swati Gautam Allahbadia 34.Paternal Leucocyte Immunization for Recurrent Pregnancy Loss. The Current Situation- Amin Gorgy amd Conor Harrity 35.IVIg treatment for Recurrent Pregnancy Loss: Yes- Genevieve Genest, Martine Boivin, Shorooq Banjar, Alyssa Hochberg, Rabea Yousef Khoudja, William Buckett, and Carl Laskin 36. Hydroxychloroquine for RPL- Shiri Weinstein and Nancy Agmon-Levin 37.Debate: Should Filgrastrim be used? Yes- Fabio Scarpellini and Marco Sbracia 38.Should Filgrastrim be used? No- Abey Eapen 39.Chinese Medicine in RPL- Aviv Messinger and Keren Sela 40. Decline in sperm quality - Dov Feldberg and Howard J. A. Carp
