Full Description
Extensively updated in light of the UK Medical Research Council's (MRC) latest guidance on complex intervention research methods in health and social care, this important book provides the most comprehensive resource available to understand and apply the range of methodologies available to researchers and practitioners today.
After an introductory chapter detailing the history of, and future challenges for, complex interventions research, and two chapters on patient and public involvement, the book is split into four discrete but interconnected parts:
Section I explores the development phase of complex interventions, covering theory building, adaptation of existing interventions, stakeholder involvement, and context consideration—setting the foundation for successful research programs.
Section II examines feasibility testing of complex interventions, addressing uncertainties in intervention design, methodology, and procedures before determining whether to stop, amend, or proceed to full evaluation.
Section III presents evaluation methodologies for complex interventions, covering trial designs, process evaluation, economic assessment, data registries, population approaches, theory-based methods, and simulation modelling.
Section IV addresses implementation science methodologies for translating complex interventions into practice, addressing theories, adaptation, hybrid designs, diffusion, and collaborative approaches.
The concluding chapter asks readers to reflect on the importance of initiating collaborative, programmatic research groups.
With a renewed focus on the context of complex interventions, including concise summaries of the latest thinking, this is essential reading for any researcher or practitioner in health and social care.
Contents
Foreword. A Brief History of The Development of the 2021 Updated Mrc Framework Guidance Document 1. An Introduction to Researching Complex Interventions in Health 2. The Theory and Practice of Patient and Public Involvement for Complex Interventions 3. The Experience of Patient and Public Involvement for Complex Interventions Section I: Developing or Identifying Complex Interventions 4. How to Develop Complex Interventions 5. Reviewing and Synthesising Quantitative Data on Complex Interventions 6. Reviewing and Synthesising Qualitative Data on Complex Interventions and Integrating in Mixed Methods Syntheses 7. Understanding the Contextual Situation for The New Complex Intervention 8. Identifying Uncertainties and Questions When Developing Complex Interventions 9. The Use of Programme Theory in Intervention Development 10. Complex Interventions: A Behaviour Change Perspective 11. Modelling Process and Outcomes in Complex Interventions Section II: Investigating the Feasibility of Complex Interventions 12. Feasibility and Pilot Studies for Complex Interventions: An Introduction 13. Addressing Uncertainties Related to Interventions Using Qualitative and Quantitative Methods 14. Using Feasibility Studies to Address Methodological and Procedural Uncertainties Prior To Clinical Trials 15. How to Calculate the Sample Size Required for Definitive Randomised Controlled Trials 16. Identification and Quantification of Progression Criteria in the Design, Conduct and Reporting of Feasibility Studies 17. Feasibility in Practice; Undertaking A Feasibility Study to Answer Procedural, Methodological and Clinical Questions Prior To a Full Scale Trial 18. Evaluability Assessments Section III: Evaluating Complex Interventions 19. Evaluating Efficacy and Effectiveness in The Context of Complex Interventions: Clinical Trial Designs, Benefits, And Shortcomings 20. Process Evaluation of Complex Interventions: Evolving Perspectives 21. Economic Evaluations of Complex Interventions 22. Additional Resources for Evaluating Complex Interventions 23. Evaluating Population-Level Health Interventions 24. Theory-Based Evaluation of Complex Health Interventions 25. Simulation Modelling to Evaluate Complex Interventions Section IV: Implementing Complex Interventions 26. The Implementation Phase: Using Implementation Science Theories, Models and Frameworks 27. Using Programme Theory and Process Evaluation to Co-Create a Local Plan to Manage Intervention Fidelity and Adaptations28. Effectiveness-Implementation Hybrid Studies to Speed the Translation of Complex Health Interventions into Practice 29. Designing Complex Health Innovations for Dissemination and Diffusion 30. An Organisational Learning and Unlearning Perspective on Implementing Complex Interventions 31. Network Interventions in Dissemination and Implementation Research 32. Integrated Knowledge Translation and Complex Interventions: Using Research Partnership to Respond to Context and Enhance Implementation 33. Challenges Facing Implementation Science Researchers 34. Concluding Thoughts; Integrating the Guidance into Your Research Programme
