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Full Description
This book introduces the field of molecular diagnostics, tracing its evolution from the earliest days of genetic research to cutting-edge advancements. It begins with a historical overview, setting the stage for an understanding of the foundational principles and techniques that underpin current practices in DNA analysis. It also provides the intricate details of various molecular techniques, such as advanced polymerase chain reaction (PCR) methods and next-generation sequencing, and their impact in the field of genetics and diagnostics. The book also explores the significant role of bioinformatics as the backbone of modern diagnostics and examines the changes brought about by high-throughput technologies and nanotechnology in molecular research and diagnostics. The importance of molecular imaging techniques in visualizing biological processes is discussed, along with the advancements in RNA analysis and their diagnostic implications. The book addresses the emerging fields of metabolomics and proteomics in molecular diagnostics and the transformative impact of artificial intelligence in this field. The book concludes with a thoughtful discussion on the ethical and regulatory considerations in molecular diagnostics. This book is intended for researchers and students of the fields of molecular diagnostics, biotechnology, and genomics.
Key Features:
Provides historical overview and recent advancements in the field of molecular diagnostics
Explores foundational principles and advanced techniques in DNA analysis, including detailed insights into PCR methods
Covers the applications and impact of next-generation sequencing in genetics and diagnostics
Discusses the revolutionary influence of high-throughput technologies and nanotechnology in molecular research and diagnostics
Examines the roles of metabolomics, proteomics, and artificial intelligence in molecular diagnostics
Contents
Chapter 1. Evolution of Molecular Diagnostics: From Genetic Foundations to Modern Technological Innovations. Chapter 2. Sample Handling in Molecular Diagnostics. Chapter 3. Polymerase Chain Reaction and Its Variants in Molecular Diagnostics. Chapter 4. CRISPR-Based Diagnostic Technologies. Chapter 5. Next-Generation Sequencing (NGS). Chapter 6. Nanotechnology-Based Diagnostics. Chapter 7. Role of AI in Molecular Diagnostics. Chapter 8. Molecular Diagnostics in Cardiovascular Diseases. Chapter 9. Advancements in Cytogenetics for Molecular Diagnostics. Chapter 10. Microfluidics and Lab-on-a-Chip Technologies. Chapter 11. Transcriptomics Analysis in Molecular Diagnostics.
