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Full Description
This book provides a comprehensive exploration of the field of molecular diagnostics, tracing its evolution from the earliest days of genetic research to cutting-edge advancements. It begins with a historical overview, setting the stage for an understanding of the foundational principles and techniques that underpin current practices in DNA analysis. It also provides the intricate details of various molecular techniques, such as advanced polymerase chain reaction (PCR) methods and next-generation sequencing, and their impact in the field of genetics and diagnostics. The book also explores the significant role of bioinformatics as the backbone of modern diagnostics and examines the revolutionary changes brought about by high-throughput technologies and nanotechnology in molecular research and diagnostics. The importance of molecular imaging techniques in visualizing biological processes is discussed, along with the advancements in RNA analysis and their diagnostic implications. The book addresses the emerging fields of metabolomics and proteomics in molecular diagnostics and the transformative impact of artificial intelligence in this field. The book concludes with a thoughtful discussion on the ethical and regulatory considerations in molecular diagnostics. This book is intended for professionals and researchers in the fields of molecular diagnostics, biotechnology, and genomics.
Key Features
Provides a thorough historical overview and recent advancements in the field of molecular diagnostics.
Explores foundational principles and advanced techniques in DNA analysis, including detailed insights into Polymerase Chain Reaction (PCR) methods.
Covers the applications and impact of next-generation sequencing, emphasizing its role in genetics and diagnostics.
Discusses the revolutionary influence of high-throughput technologies and nanotechnology in molecular research and diagnostics.
Examines new areas like metabolomics, proteomics, and the transformative role of artificial intelligence in molecular diagnostics.
Contents
Chapter 1. Evolution of Molecular Diagnostics: From Genetic Foundations to Modern Technological Innovations. Chapter 2. Sample Handling in Molecular Diagnostics. Chapter 3. Polymerase Chain Reaction and Its Variants in Molecular Diagnostics. Chapter 4. CRISPR-Based Diagnostic Technologies. Chapter 5. Next-Generation Sequencing (NGS). Chapter 6. Nanotechnology-Based Diagnostics. Chapter 7. Role of AI in Molecular Diagnostics. Chapter 8. Molecular Diagnostics in Cardiovascular Diseases. Chapter 9. Advancements in Cytogenetics for Molecular Diagnostics. Chapter 10. Microfluidics and Lab-on-a-Chip Technologies. Chapter 11. Transcriptomics Analysis in Molecular Diagnostics.