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Full Description
The present book describes the common human diseases caused by the blood-infecting protozoans, and their diagnosis and treatment. This book compiles the latest literature on the genetic diversity, therapeutics, and drug resistance in protozoan parasites, with a focus on malaria parasites: Plasmodium falciparum and Plasmodium vivax. It explores the association of parasite genetic makeup with drug resistance. The book covers the mechanisms of drug resistance, its spread, and factors affecting drug resistance. The book facilitates research, design, and development of therapeutics against malarial parasites. The book is meant for post-graduate students of microbiology, parasitology, and medicine, as well as healthcare workers, medical practitioners, public health staff, and policymakers.
Key Features:
Describes the recent updates on how the different protozoan parasites cause human diseases
Includes the genomics and epidemiology of important protozoan parasites such as Plasmodium, Trypanosoma, Leishmania, and Toxoplasma, and covers the role of nanotechnology in the diagnosis and treatment of the diseases
Covers the detection of drug resistance and its spread in blood-infecting protozoan parasites
Discusses the molecular basis of antimalarial drug resistance in Plasmodium vivax
Reviews the factors contributing to the spread of resistance in malaria parasites
Contents
1. Current updates on the causes of human diseases resulting from protozoan parasites. 2. Understanding the genomics and epidemiology of common protozoan diseases. 3. Diagnosis and treatment of protozoan diseases: an update. 4. Nanotechnology in diagnosis and treatment of protozoan diseases. 5. The emergence and spread of drug resistance in blood infecting protozoans: a major threat to human health. 6. Mechanism of drug resistance and treatment failure in Leishmaniasis, trypanosomiasis, Toxoplasma gondii and Babesia. 7. Investigation of sesquiterpene lactone endoperoxides and associated genetic markers for drug resistance in P. falciparum. 8. Drug resistance marker for Amino alcohols, Aminoquinolines, and antifolates in P. falciparum. 9. Molecular basis of antimalarial drug resistance in Plasmodium sp., current challenges and future perspectives. 10. Unmasking influential factors in malaria drug resistance transmission. 11. Detection of resistance: assessing in vivo and in vitro drug resistance in malaria parasite. 12. Monitoring of Plasmodium Genetic Diversity and Drug Resistance Can Be an Effective Tool for Malaria Elimination in Resource-Limited Endemic Regions.
