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Full Description
This book discusses the inherent need for and significance of metal ions in metabolic reactions. It details their essential elements and mechanistic prospects in regulating biological reactions, as well as covers the broad domain of elements, including main group as well as transition elements, in a comparative and comprehensive manner. Contemporary and advanced topics, such as nuclear medicine and biomineralization, are also covered.
Features:
Highlights the different behaviors of Fe/Cu proteins and the structural changes during their biological functioning
Discusses the mechanistic prospects of various enzymes and proteins, e.g., Cu‑Zn SOD, zinc finger, and ionophores
Explores the chemical and biological prospects of trace and ultra‑trace elements
Includes biomimetic models of iron and copper
Reviews the criteria for nature selecting metal ions, why only certain elements are essential, and the differences between biologically induced and biologically controlled biomineralization
This book is aimed at graduate students and researchers in chemical engineering, materials science, chemistry, and biological sciences.
Contents
1. Role of Metal Ions in Biology: An Overview 2. Basic Principles of Coordination Chemistry 3. Biochemistry of Alkali and Alkaline Earth Metals 4. Biological Relevance of Iron: Uptake, Electron Transfer and Transport 5. Role of Cobalt in Biology 6. Biochemistry of Nickel 7. Bioinorganic Prospect of Copper-Containing Enzymes 8. Biochemistry of Zinc 9. Metal Ions in Diagnostics and Therapeutics 10. Biomineralization