化学プロセス研究開発ハンドブック（第２版）<br>Handbook for Chemical Process Research and Development, Second Edition （2ND）

個数：
電子版価格
¥39,284
  • 電子版あり

化学プロセス研究開発ハンドブック（第２版）
Handbook for Chemical Process Research and Development, Second Edition （2ND）

  • 在庫がございません。海外の書籍取次会社を通じて出版社等からお取り寄せいたします。
    通常6～9週間ほどで発送の見込みですが、商品によってはさらに時間がかかることもございます。
    【重要ご説明事項】
    1. 納期遅延や、ご入手不能となる場合がございます。
    2. 複数冊ご注文の場合は、ご注文数量が揃ってからまとめて発送いたします。
    3. 美品のご指定は承りかねます。

    ●3Dセキュア導入とクレジットカードによるお支払いについて
  • 【入荷遅延について】
    世界情勢の影響により、海外からお取り寄せとなる洋書・洋古書の入荷が、表示している標準的な納期よりも遅延する場合がございます。
    おそれいりますが、あらかじめご了承くださいますようお願い申し上げます。
  • ◆画像の表紙や帯等は実物とは異なる場合があります。
  • ◆ウェブストアでの洋書販売価格は、弊社店舗等での販売価格とは異なります。
    また、洋書販売価格は、ご注文確定時点での日本円価格となります。
    ご注文確定後に、同じ洋書の販売価格が変動しても、それは反映されません。
  • 製本 Hardcover:ハードカバー版／ページ数 866 p.
  • 言語 ENG
  • 商品コード 9781032259277
  • DDC分類 615.19

Full Description

This fully updated second edition reflects the significant changes in process chemistry since the first edition and includes more common process issues such as safety, cost, robustness, and environmental impact. Some areas have made notable progress such as process safety, stereochemistry, new reagents and reagent surrogates. Forty years ago there were few process research and development activities in the pharmaceutical industry, partly due to the simplicity of drug molecules. With increasing structural complexity especially the introduction of chiral centers into drug molecules and stricter regulations, process R&D has become one of the critical departments for pharmaceutical companies.

Features:

This unique volume now in its second edition is designed to provide readers with an unprecedented strategy and approach which will help chemists and graduate students develop chemical processes in an efficient manner.
Promotes an industrial mindset concerning safety and commercial viability when developing methods.
The author discusses development strategies with case studies and experimental procedures.
Focuses on mechanism-guided process development which provides readers with practical strategies and approaches.
Addresses more common process issues such as safety, cost, robustness, and environmental impact.
This book provides a new direction for scientists, researchers, and students in materials science and polymer chemistry who seek to better understand the chemistry behind conducting polymers and improve their performance for use in advanced energy applications.

Contents

1. Reaction solvent selection

2. Reagent selection

3. Various reagent surrogates

4. Modes of reagent addition -control of impurity formation

5. Process optimization with additives

6. Process optimization of catalytic reactions

7. Process optimization of problematic reactions

8. Hazards of oxidation and reduction reactions

9. Other hazardous reactions

10. Hazardous reagents

11. Grignard reagent and related reactions

12. Challenging reaction intermediates

13. Protecting groups

14. Telescope approach

15. Design of new synthetic route

16. Stereochemistry

17. Various quenching strategies

18. Various isolation and purification strategies

19. Methods for residual metal removal

20. Methods for impurity removal

21. Pharmaceutical salts

22. Solid form