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Full Description
This textbook shows readers how models of the genetic processes involved in evolution are made (including natural selection, migration, mutation, and genetic drift in finite populations), and how the models are used to interpret classical and molecular genetic data.
The material is intended for advanced level undergraduate courses in genetics and evolutionary biology, graduate students in evolutionary biology and human genetics, and researchers in related fields who wish to learn evolutionary genetics. The topics covered include genetic variation, DNA sequence variability and its measurement, the different types of natural selection and their effects (e.g. the maintenance of variation, directional selection, and adaptation), the interactions between selection and mutation or migration, the description and analysis of variation at multiple sites in the genome, genetic drift, and the effects of spatial structure.
Contents
1. Variability and its measurement.- 2. Basic selection theory and the maintenance of variation.- 3. Directional selection and adaptation.- 4. Migration, mutation and selection.- 5. The evolutionary effects of finite population size: basic theory.- 6. Molecular evolution and variation.- 7. Genetic effects of spatial structure.- 8. Multiple sites and loci.- 9. The evolution of breeding systems, sex ratios and life histories.- 10. Some Topics in Genome Evolution.- Mathematical and Statistical Appendix.
