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Full Description
Thoroughly revised and updated, this fifth edition of the text seeks to reflect the ongoing revolutions and developments in this field. The emphasis of the book is now placed on the roles of paracrine factors in development.
Contents
An introduction to animal development; genes and development; the cellular basis of morphogenesis - differential cell affinity; fertilization - beginning a new organism; cleavage - creating multicellularity; gastrulation - reorganizing the embryonic cells; early vertebrate development - mesoderm and endoderm; transcriptional regulation of gene expression; transcriptional regulation of gene expression - the activation of chromatin; control of developmental by differential RNA processing and translation; autonomous cell specification by cytoplasm determinants; the genetics of axis specification in drosophila; specification of cell fate by progressive cell-cell interactions; establishment of the body axes in mammals and birds; proximate tissue interactions - secondary induction; development of the tetrapod limb; cell interactions at a distance - hormones as mediators of development; sex determination; environmental regulation of animal development; the saga of the germ line; developmental mechanisms of evolutionary change.
