Full Description
Clinical Research in Oral Health surveys the essentials of clinical research in oral health, anchoring these principles within the specific context of the oral health arena. Addressing research questions exclusively applicable to dentistry and oral health, the book thoroughly illustrates the principles and practice of oral health clinical research. Clinical Research in Oral Health also clarifies the framework of regulatory issues and presents emerging concepts in clinical translation, relating the research principles to clinical improvement.
Contents
1 Clinical and Translational Research: Implications in the Promotion of Oral Health William V. Giannobile
2 Ethics in Oral Health Research
Elizabeth Ripley, Francis L. Macrina
3 Responsibilities of Institutions and Individuals in Clinical Research in the Oral Health Sciences
Gary C. Armitage
4 Regulatory Process for the Evaluation of Dental Drugs, Devices and Biologics
Darnell Kaigler, Kay Fuller, William V. Giannobile
5 Clinical and Translational Research Grantsmanship: Funding Opportunities and Obtaining Research Support
Bruce L. Pihlstrom, Michael L. Barnett
6 Data Management in Oral Health Research
Bruce A. Dye, Jules T. Mitchel
7 Hypothesis Testing and Avoiding False-Positive Conclusions
Philippe P. Hujoel
8 Outcomes in Oral Health Research
Amid I. Ismail
9 Examiner Training: Standardization and Calibration in Periodontal Studies
Niklaus P. Lang, Mary P. Cullinan, Douglas W. Holborow, Lisa J.A. Heitz-Mayfield
10 Observational Studies in Oral Health Research
Hal Morgenstern, Woosung Sohn
11 Initial Clinical Trials Allow Assessment of Safety, Dosing and Preliminary Efficacy Prior to Large Randomized Controlled Pivotal Studies
Jules T. Mitchel, Glen Park, Mark Citron, Russ Pagano, Leslie Wisner-Lynch, Samuel E. Lynch
12 Phase III Pivotal Clinical Trials: Clinical Decision-making
Norman S. Braveman, Bryan Michalowicz
13 Post-Marketing Surveillance
Eugenio D. Beltran-Aguilar, Michael C. Manz
14 Dental Practice-Based Research Networks
Donald J. DeNucci and the CONDOR Dental Practice-based Research Networks
15 The Technology Transfer Process for Life Science Innovations in Academic Institutions
Robert J. Genco
16 Adoption of New Technologies for Clinical Practice
Maxwell H. Anderson
17 Publication of Research Findings
James Bader
18 The Evidence-base for Oral Health
Helen Worthington, Ian Needleman, Anne-Marie Glenny
