Full Description
This book, the proceedings of Falk Symposium 98 held in Titisee, Germany, 25-26 May 1997, provides more depth in the field of extraintestinal manifestations of IBD, which gastroenterologists frequently see, but which require close contact with other subspecialities. Further, the basic understanding of the pathophysiology of extraintestinal manifestations clearly needs 'upgrading', based on recent advances in animal models or clinical investigation. While the intestinal manifestations of IBD are increasingly well characterized, the extraintestinal facets of IBD currently are best understood on the basis of sophisticated clinical description, thorough investigation and an excellent clinical standing. Modern techniques in immunology, microbiology, pathobiochemistry and new horizons in imaging methods as well as in surgery, however, have substantially contributed to this knowledge, and thus the book will foster a mutual exchange between the basic or theoretical disciplines and clinicians, including a variety of different subspecialities in order to stimulate clinical and theoretical research topics. Accordingly, the book embraces both aspects: current knowledge on extraintestinal manifestations of IBD as well as a definition of objectives and a path for future steps in research at the end of this millennium.
Contents
Preface. 1. State of the Art Lecture; S.R. Targan. Section Iand Psychiatry of IBD. 2. Pain in Inflammatory Bowel Disease: Mechanisms, Perception and Control; L. Chang, E.A. Mayer. 3. Peripheral and Central Neurological Complications of IBD; V. Gross. 4. Inflammatory Bowel Disease - Behavioral and Psychoimmunologic Aspects; D.A. Drossman. Section II: IBD-Associated Neuroendocrine and Musculo-Skeletal Disorders. 5. Neuroendocrine Pathologies in IBD: Epiphenomenon or Pathophysiological Key? T.R. Koch, et al. 6. Arthritis, Osteoporosis and Rheumatologic Manifestations: Patterns, Diagnostic and Therapeutic Problems; M. De Vos, et al. Section III: The Skin and Eye in IBD. 7. Cutaneous Manifestations of IBD and IBD- Associated Inflammatory Lesions; F.R. Ochsendorf. 8. Ocular Manifestations of Inflammatory Bowel Disease; M. Krause, K.W. Ruprecht. Section IV: Bronchopulmonary and Cardiovascular Involvement in IBD: Manifestations and Drug Effects. 9. IBD and the Respiratory Tract; R. Buhl. 10. Cardiovascular Involvement in Inflammatory Bowel Diseases: Manifestations and Drug Effects; W. Petritsch. 11. Mortality in IBD Role of Disease Activity, Complications and Malignancy; V. Binder. Section V: Systemic Gastrointestinal Manifestations of IBD. 12. Primary Sclerosing Cholangitis: Diagnosis, Natural History and Management; R. Chapman. 13. Systemic Manifestations of Inflammatory Bowel Diseases: Non-PSC Hepatobiliary Complications; U. Leuschner. 14. Pancreatitis in IBD; H. Goebell. 15. Disorders of GI Tract Motility in IBD: From Belief to Relief; S.F. Phillips. Section VI: Haematological and Clotting Disorders. 16. Anemia in Inflammatory Bowel Disease Diagnosis and Treatment; S. Schreiber, S. Wedel. 17. Pathophysiological Role of the Kallikrein- Kinin System in Experimental Enterocolitis; R.W. Colman. Section VII: Nutrition and Metabolism. 18. The Smaller the Patient, the Bigger the Problems; K.J. Motil. 19. Malabsorption of Nutrients and Malnutrition in Inflammatory Bowel Disease; J. Stein, F. Menge. 20. Amyloidosis, Collagen Formation and Fibrosis in IBD: Pathophysiology, Presentation and Therapeutic Concepts; A. Stallmach, K. Hohloch. 21. The Concept of Luminal Nutrition &endash; the Importance of Colonic Function as Small Bowel Failure Proceeds; I. Nordgaard. 23. The Genetics of IBD; J.I. Rotter. Section VIII: IBD and the Urogenital System. 24. Reproductive Aspects of Inflammatory Bowel Disease; S.D. Craigo. 25. Urolithiasis in IBD: B. Lembcke. 26. Effect of Aminosalicylates on Renoparenchymal Function in IBD Patients; W. Kreisel, et al. 27. Oral Steroids for `Topical' Therapy of IBD: How does the Tailored Regimen Fit? P. Rutgeerts. Section IX: Immunology. 28. Viral and Bacterial Infections; R.B. Sartor. 29. The Role of Intestinal Lymphoblast Homing, Endothelial Cell Adhesion and Cytokine Secretion in the Organ Specific, Inflammation Related Extraintestinal Manifestations of Inflammatory Bowel Disease; R.P. MacDermott. 30. Mucosal Immunity and Immune- Mediated Injury in Crohn's Disease &endash; Relevance of Disease Distribution; A. Ferguson, S. Ghosh. 31. Is Increased Intestinal Permeability in IBD Pathogenic? H. Lochs. 32. Small Intestinal Transplantation &endash; The Ultimate Therapy for Inflammatory Bowel Disease? E.M.M. Quigley. 33. Inflammatory Bowel Disease and Carcinoma: Risks and Surveillance Strategies; E.F. Stange. Section X: Surgical Problems in IBD. 34. Management of Anorectal Fistula; M. Starlinger. 35. Life with Pouch or Stoma; M. Kettlewell. 36. Management of Ileo-Anal Pouch Related Disorders; H.J. Buhr. Section XI: IBD Complications at the Pelvic Floor Level: Standards and Beyond. 37. Role of Endoscopy in Pelvic (Peri)Intestinal Disease; G.N.J. Tytgat. 38. Is There Anything Better than Radiology, MRI and Nuclear Medicine? A. Rieber, H.-J. Brambs. 39. Inflammatory Bowel Disease &endash; Complications at the Pelvic Floor Level: Laboratory Tests and Measures of Motility &endash; Are They of Any Help? Wehrmann, et al. 40. Alternative and Traditional Methods in IBD: What is Practiced, What is Published, What is Noteworthy? A. Gangl. Index.
