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Full Description
This is the authoritative introduction to the concepts and techniques of recombinant DNA research and their dramatic results. The book explores core concepts in molecular biology in a contemporary inquiry-based context, building its coverage around the landmark experiments that redefined our understanding of DNA. As a result, students learn how working scientists make real high-impact discoveries. Included are chapters on applications to human diseases, cancer, and forensics.
Contents
Foundations of DNA.- Overview.- DNA is the Primary Genetic Material.- From DNA to Protein.- Basics of Gene Expression.- Basic Tools of Recombinant DNA.- Fundamental Features of Genes.- Getting DNA into Cells and Organisms.- Moveable Elements.- Epigenetics.- RNAi.- Foundations of Genomics.- Overview.- Sequencing a Small Genome.- How the Human Genome was Sequenced.- Analyzing Genomes.- Overview.- Sequence Analysis.- Genome-wide Functional Analysis.- Genomic Approaches to Human Biology.- Hunting Human Disease Genes.- Cancer Genomics.- DNA and Justice.
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