Full Description
The two volumes of this work examine the effectiveness of different cancer treatment modalities as applied under a range of individual conditions and, further, discusses the behaviour of residual tumours that survive such treatments. Serving as both a source of information and a guide to future research, this work deals with pre-clinical tumours, covering the short and long-term consequences of various techniques on both the host patient and the carcinoma itself. Among the many pre-clinical issues discussed in Part A are kinetics, growth factors, metastases and immunity, and genetic regulation. Part B treats clinical aspects such as biological response modifiers, radiobiology, autologous bone marrow transplantation and more.
Contents
Partial table of contents:; BIOLOGICAL RESPONSE MODIFIERS; Tumor Treatment and Cytokines (J. Schrader, et al.); Towards Improved Cancer Therapy Using Subcutaneously Administered Hemopoietic Colony Stimulating Factors (G. Morstyn, et al.); Mechanisms of Action of Interferon (H. Ozer); RADIOBIOLOGY; The Growth Kinetics of Clonogenic Tumor Cells That Survive Radiation Therapy (R. Kallman & C. Hughes); Microenvironmental Changes in Irradiated Tumors (S. Rockwell & C. Hughes); CLINICAL ASPECTS OF THERAPY--INTEGRATION OF DOSE INTENSITY KINETICS AND BIOLOGY WITH TREATMENT PLANNING; Modeling the Effect of Chemotherapy Intensity (C. Coppin, et al.); Comments on Kinetics and Biology of the Residual Cancer, and on Relevant Therapeutic Strategies Based on These Phenomena (J. Ragaz); AUTOLOGOUS BONE MARROW TRANSPLANTATION; Autologous Bone Marrow Transplantation for Hematologic Cancer (G. Phillips); Use of Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) to Support Intensive Chemotherapy (H.-G; Klingemann); CONSEQUENCES OF THERAPY; Induction of Secondary Neoplasms by the Treatment of Malignant Disease: Lessons from Hodgkin's Disease (J. Connors); Overview of Adjuvant Radiotherapy for Breast Cancer (J. Cuzick); Chemotherapy Schedules: Impact on Treatment Outcomes and Quality of Life (M. Tattersall); SUMMARY; Index.
