Full Description
Smell and Taste, Volume 164 focuses on recent clinical research regarding two of our primary chemical senses, smell and taste. This volume is the most comprehensive neurology book on disorders of smell and taste function. Its major sections include epidemiology, anatomy and physiology, and clinical assessment, including neuroimaging, clinical conditions affecting smell and taste function (e.g., autoimmune disorders, head trauma, diseases of the nose and mouth, etc.). The widespread use of olfactory testing in clinical trials searching for biomarkers of neurodegenerative diseases is reviewed, along with evidence that smell dysfunction can be an early marker in neurodegenerative diseases and autoimmune disorders.
Contents
SECTION I. BASIC PRINCIPLES
A. Fundamentals
1. Epidemiology of smell and taste dysfunction
B. Morphophysiology of the olfactory and nasal trigeminal sensory systems
2. Anatomy of the olfactory system
3. Development of the human olfactory system
4. Anatomy of the olfactory mucosa
5. Olfactory receptor function
6. Central olfactory structures
7. Taste and smell processing in the brain
8. The intranasal trigeminal system
9. Cranial nerve 13
C. Morphophysiology of the gustatory and oral trigeminal systems
10. Anatomy and development of the human taste system
11. Taste receptor function
12. Central taste anatomy and physiology
13. The orotrigeminal system
SECTION II. CLINICAL ASPECTS
A. Clinical assessment
14. Health histories and medical evaluations of patients with complaints of chemosensory dysfunction
15. Psychophysical testing of smell and taste function
16. Electrophysiological assessment of olfactory and gustatory function
17. Neuroimaging of smell and taste
B. Diseases and disorders
18. Diseases of the nasal cavity
19. Neurolocalization of taste disorders
20. Chemosensory dysfunction in neurodegenerative diseases
21. Systemic diseases and disorders
22. Toxic exposures and the senses of taste and smell
23. The influence of head injury on olfactory and gustatory function
24. Animal models of olfactory dysfunction in neurodegenerative diseases
C. Treatment and management of chemosensory disorders
25. Treatments for smell and taste disorders: A critical review
