Full Description
Histone Deacetylases in Neurodegenerative Disease, Part B, Volume 734 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on timely topics surrounding the Interaction of HDAC6 ZnF UBP with Tau affects its stability by NMR and Simulation studies, Protocols for In Vitro Analysis of Liquid-Liquid Phase Separation of Proteins, Histone deacetylases in NS, Histone Deacetylase 6 ZnF UBP domain enhances podosome formation in neuronal cells studied by high-resolution confocal microscopy, Methodological approach to Investigate Peroxiredoxin 1 Deacetylation by Histone Deacetylase 6, Critical structural features of HDAC11 inhibitors, and much more.
Additional chapters in this release include Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration, Elucidation of Site-Specific Ubiquitination on Chaperones in Response to Mutant Huntingtin, Protein acetylation dynamics (histone and non-histone) and role protein deacetylases in disease, Epigenetic Clues: Predicting Maternal Depression Through DNA Methylation, A short guide on in vivo transfection of flag-HDAC4 in dentate gyrus for study of adult neurogenesis in brain trauma, Decoding the Acetylation Journey from Neural Crest to Melanocyte, and more.
Contents
1. Interaction of HDAC6 ZnF UBP with Tau affects its stability by NMR and Simulation studies
Subashchandrabose Chinnathambi
2. Protocols for In Vitro Analysis of Liquid-Liquid Phase Separation of Proteins
Timir Tripathi and Niharika Naga
3. Histone deacetylases in NS
Chandrima Das
4. Histone Deacetylase 6 ZnF UBP domain enhances podosome formation in neuronal cells studied by high-resolution confocal microscopy
Subashchandrabose Chinnathambi
5. Methodological approach to Investigate Peroxiredoxin 1 Deacetylation by Histone Deacetylase 6
Aparna Banerjee Dixit
6. Critical structural features of HDAC11 inhibitors
Shovanlal Gayen, Indrasis Dasgupta and Srijoni Sinha
7. Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration
Marco Prinz
8. Elucidation of Site-Specific Ubiquitination on Chaperones in Response to Mutant Huntingtin
Prasad Kasthuri, Ayush Nigam, Prasun Kumar Bhunia and Trayambak Basak
9. Protein acetylation dynamics (histone and non-histone) and role protein deacetylases in disease
Devyani Haldar
10. Epigenetic Clues: Predicting Maternal Depression Through DNA Methylation
Kuppan Gokulakrishnan
11. A short guide on in vivo transfection of flag-HDAC4 in dentate gyrus for study of adult neurogenesis in brain trauma
Rajaneesh Kumar Gupta
12. Decoding the Acetylation Journey from Neural Crest to Melanocyte
Vivek T. Natarajan
13. Histone deacetylase inhibition mitigates cognitive deficits and astrocyte dysfunction induced by amyloid-β (Aβ) oligomers
Flávia Carvalho Alcantara Gomes
14. Simvastatin Restores HDAC1/2 Activity and Improves Behavioral Deficits in Angelman Syndrome Model Mouse
Nihar Ranjan Jana
15. Methodology and Application of ChiP in studying translational dysregulation neurological disorders
Sumana Chakravarty
16. Insights into the epigenetic mechanisms involving histone lysine methylation and demethylation in ischemia induced damage and repair has therapeutic implication
Anant Bahadur Patel
17. TBD
Samir Patra
18. TBD
Sushabhan Sadhukhan
19. Methodological Frameworks to Probe Histone Acetylation-Driven Circuit Plasticity in SYNGAP1-Associated Neurodevelopmental Disorders
Tapas K. Kundu
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