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Full Description
Epigenetic Therapy by Phytochemicals in Lung Cancer provides a comprehensive exploration of the intersection between cancer epigenetics and phytotherapy, focusing on lung cancer. The book emphasizes the role of epigenetic alterations in cancer progression and presents phytochemicals as promising agents capable of reversing these changes, thereby offering innovative therapeutic strategies. The content examines the mechanisms by which epigenetic modifications, such as DNA methylation and histone modification, contribute to lung cancer. It details specific phytochemicals—like curcumin, resveratrol, and quercetin—and their potential to modulate these pathways, while discussing clinical applications, challenges, and future research directions. For academics, this book equips researchers and healthcare professionals with evidence-based insights into alternative cancer therapies, enhancing understanding of multi-targeted approaches. It serves as a valuable reference for teaching and further research, promoting a more inclusive perspective in cancer care and addressing disparities in treatment access and efficacy.
Contents
Section I: Introduction to Lung Cancer and Epigenetics
1. Lung Cancer: Epidemiology, Pathophysiology, and Current Therapies
2. The Role of Epigenetic Alterations in Lung Cancer Progression
3. Epigenetic Therapy: Overview and Emerging Frontiers
Section II: Phytochemicals as Epigenetic Modulators
4. Introduction to Phytochemicals with Epigenetic Activity
5. DNA Methylation Modulation by Phytochemicals
6. Histone Modification Regulation by Plant-based Compounds
7. Impact of Phytochemicals on Non-coding RNAs in Lung Cancer
Section III: Phytochemicals in Lung Cancer Therapy - Mechanisms and Evidence
8. Polyphenols as Epigenetic Modulators: Curcumin, Resveratrol, and Quercetin
9. Flavonoids and Epigenetic Therapy in Lung Cancer
10. Terpenoids and Their Role in Lung Cancer Epigenetic Modulation
11. Alkaloids and Lung Cancer Epigenetics: Mechanistic Insights and Case Studies
Section IV: Clinical Implications and Future Directions
12. Preclinical and Clinical Trials of Phytochemicals in Lung Cancer Epigenetics: •
13. Insights into clinical trials and real-world applications of phytochemicals
14. Challenges in Phytochemical-based Epigenetic Therapy
15. Formulation and Delivery Systems for Phytochemical-based Epigenetic Drugs
16. Combination Therapies: Phytochemicals with Conventional Lung Cancer Therapies
17. Conclusion and Future Perspectives in Epigenetic Phytotherapy for Lung Cancer
18. Cancer immunotherapy, including CAR-T cell therapy and immune checkpoint inhibitors
