Full Description
Cytokines of the Immune System: The Role of Cytokines in Disease Related to Immune Response, Second Edition is a comprehensive and essential resource for graduate and postgraduate training of physicians, dentists, biomedical specialists, and those interested in scientific research in biology and biochemistry. The book provides an up-to-date, textbook-like description of immunology, focusing on the critical role of cytokines in immune responses. With advancements in cytokine research and signal transduction, this new and improved edition offers a deeper understanding of cytokine-receptor interactions, supported by novel figures based on crystal-structure conformations from the protein database.
These insights are invaluable for inspiring new drug designs and therapeutic strategies. The book delivers a thorough overview of immunology, detailing the development and regulation of the immune system, with a special focus on cytokines. It presents an upgraded description of interleukins, immune-modulatory cytokines, and chemokines, exploring their structure, sources, functions, receptors, disease associations, and therapeutic potentials. This edition also introduces the latest information on innate lymphoid cells and their cytokines, as well as their adaptive immunity counterparts. A dedicated chapter on the cytokine storm provides critical insights into this phenomenon.
Contents
1. Introduction: Common Features About Cytokines
2. The Immune System: Definition and Development of Immunity
3. Activation of Cells of the Immune System
4. The Role and Regulation of the Immune Responses
5. Innate Immunity Cytokines with Pro- and Anti-inflammatory Activities
6. Innate Immunity Cytokines with Antiviral Properties: Interferons
7. Cytokines Shaping Adaptive T and B Cell Responses
8. Chemokines: Cytokines Controlling Cellular Migrations
9. Cytokine Networks and Cytokine Storm
10. Theories About the Function of the Immune System
