Full Description
Cytokines of the Immune System: The Role of Cytokines in Disease Related to Immune Response, Second Edition is a comprehensive and essential resource for graduate and postgraduate training of physicians, dentists, biomedical specialists, and those interested in scientific research in biology and biochemistry. The book provides an up-to-date, textbook-like description of immunology, focusing on the critical role of cytokines in immune responses. With advancements in cytokine research and signal transduction, this new and improved edition offers a deeper understanding of cytokine-receptor interactions, supported by novel figures based on crystal-structure conformations from the protein database. These insights are invaluable for inspiring new drug designs and therapeutic strategies. The book delivers a thorough overview of immunology, detailing the development and regulation of the immune system, with a special focus on cytokines. It presents an upgraded description of interleukins, immune-modulatory cytokines, and chemokines, exploring their structure, sources, functions, receptors, disease associations, and therapeutic potentials. This edition also introduces the latest information on innate lymphoid cells and their cytokines, as well as their adaptive immunity counterparts. A dedicated chapter on the cytokine storm provides critical insights into this phenomenon.
Key features of Cytokines of the Immune System: The Role of Cytokines in Disease Related to Immune Response, Second Edition include upgraded chapter content throughout, enhanced connections between cytokines and diseases, and a historical overview of cytokines pivotal in polarizing immune responses. The book also promotes new therapeutic options for each cytokine or cytokine family, displayed in detailed figures that serve as summaries or guides for treatment decision-making in various diseases, including cancer, infections, and autoimmune disorders. This expanded edition is a vital tool for anyone seeking to understand the latest developments in cytokine research and their implications for immunotherapy.
Contents
1. Introduction: Common Features About Cytokines
2. The Immune System: Definition and Development of Immunity
3. Activation of Cells of the Immune System
4. The Role and Regulation of the Immune Responses
5. Innate Immunity Cytokines with Pro- and Anti-inflammatory Activities
6. Innate Immunity Cytokines with Antiviral Properties: Interferons
7. Cytokines Shaping Adaptive T and B Cell Responses
8. Chemokines: Cytokines Controlling Cellular Migrations
9. Cytokine Networks and Cytokine Storm
10. Theories About the Function of the Immune System
