Full Description
Pesticides and Neurotoxicant Exposures: Impacts of Neurodevelopment and Long-Term Brain Health explores neuroscience research, revealing how chronic pesticide exposure contributes to neurodegenerative diseases and cognitive decline. This new volume synthesizes findings on the mechanisms of pesticide-induced neurotoxicity and its impact on brain health. Targeted at researchers, clinicians, and policymakers, the book explores gaps in knowledge and the urgent need for improved regulation to protect vulnerable populations. By bridging scientific insights with public health, the book aims to advance understanding and prevention of pesticide-related neurological disorders.
Contents
Section 1: Introduction to Pesticides and Neurotoxicity
1. Pesticides and Human Health: An Overview
2. Neurotoxic Effects of Pesticides: Mechanisms and Pathways
3. Classification of Pesticides and Their Neurotoxic Potential
4. Routes of Pesticide Exposure and Bioaccumulation
5. Epidemiological Evidence of Pesticide-Induced Neurotoxicity
Section 2: Pesticides Classes and Their Neurotoxic Effects
6. Organophosphates and Acetylcholinesterase Inhibition
7. Carbamates: Mechanisms of Neurotoxicity
8. Organochlorines and Their Impact on the Nervous System
9. Pyrethroids: Effects on Ion Channels and Neurotransmission
10. Neonicotinoids and Their Influence on the Central Nervous System
11. Herbicides and Neurodegeneration: The Case of Paraquat and Glyphosate
12. Fungicides and Neurotoxicity: A Neglected Risk?
13. Rodenticides and Their Impact on Brain Function
14. Biopesticides: Safer Alternatives or Hidden Neurotoxins?
Section 3: Cellular and Molecular Mechanisms of Pesticide-Induced Neurotoxicity
15. Oxidative Stress, Reactive oxygen species and Mitochondrial Dysfunction in Pesticide Toxicity
16. Neuroinflammation and Glial Cell Activation in Pesticide Exposure
17. Neurotransmitter Dysregulation Induced by Pesticides
18. Epigenetic Modifications in Pesticide-Induced Neurotoxicity
19. Blood-Brain Barrier Disruption Mechanisms by Pesticides
20. Autophagy, Apoptosis, and Cell Death Pathways in Pesticide Toxicity
Section 4: Pesticides and Neurodevelopmental Disorders
21. Prenatal and Early-Life Pesticide Exposure: Impacts on Brain Development
22. Pesticides and Autism Spectrum Disorders: Evidence and Mechanisms
23. Attention Deficit Hyperactivity Disorder (ADHD) and Pesticide Exposure
24. Pesticides and Cognitive Impairments in Children
Section 5: Pesticides and Neurodegenerative Diseases
25. Pesticides and Alzheimer's Disease: Risk Factors and Mechanisms
26. Parkinson's Disease and Pesticide Exposure: A Strong Association?
27. Amyotrophic Lateral Sclerosis (ALS) and Neurotoxicity of Pesticides
28. Multiple Sclerosis and Pesticides: Possible Links
Section 6: Biomarkers and Detection of Pesticide-Induced Neurotoxicity
29. Biomarkers of Pesticide Exposure in the Nervous System
30. Neuroimaging, Computational and Artificial Intelligence Approaches in Pesticide Toxicity Assessment
31. Advances in Toxicogenomics for Evaluating Pesticide-Induced Neurotoxicity
Section 7: Mitigation Strategies and Future Directions
32. Precision agriculture and Artificial Intelligence driven pest management to reduce pesticide dependency
33. Detoxification Pathways and Neuroprotection Against Pesticides
34. Dietary and Nutritional Interventions for Reducing Neurotoxic Effects
35. Regulatory Policies and Risk Assessment of Neurotoxic Pesticides
36. Eco-Friendly Alternatives: Reducing the Neurotoxic Burden of Pesticides
37. Public Awareness and Education on Pesticide Neurotoxicity
38. Novel Therapeutic Strategies for Pesticide-Induced Neurotoxicity
39. Innovations in Pesticide Formulation for Reduced Neurotoxicity
40. Artificial Intelligence and Big Data in Neurotoxicology Research
41. Future Perspectives on Pesticide Use and Neurotoxic Risks
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