Full Description
Cytokine-Based immunotherapy: Part B, Volume 401 delves into the intricate world of cytokines, the vital signaling proteins that orchestrate the immune response and their pivotal role in modulating various immune functions. From fundamental mechanisms to their therapeutic applications, this book offers a thorough examination of the latest trends and developments in leveraging cytokines for immunotherapy. Chapters cover Cytokine-based immunotherapy in pancreatic cancer, IL-33 and its pleiotropic role in cancer, Immunocytokines based on IL-12 for cancer therapy: enhancing efficacy and reducing toxicity, Cytokine network in immunosuppression and tumor development in glioblastoma, The Double-Edged Role of Interferon Gamma in Cancer Immunity, and much more.
An additional section covers Engineering Interleukin-10 for Therapeutic Applications, IL-23 Blockade: A Strategy for Relieving Inflammatory Diseases. Targeting TNF-alpha examines the immunotherapeutic approach for alleviating neuropathic pain. The key role of immunomodulatory cytokines for the development of novel nk cell-based cancer therapies focuses on the importance of cytokines in developing new cancer treatments. Finally, complexities in the clinical development of TGFβ inhibitors covers the challenges in creating inhibitors for TGFβ.
Contents
1. Cytokine-based immunotherapy in pancreatic cancer
Flor Navarro, Andres Gordo Ortiz and Ines ortiz de Solorzano
2. IL-33 and its pleiotropic role in cancer
Nicolas Jacquelot
3. Immunocytokines based on IL-12 for cancer therapy: enhancing efficacy and reducing toxicity
Cristian Smerdou Sr., Uxue Beloki, Laura Salaberry, Ángela Covo-Vergara, Carla Ortuño-Moya and Noelia Silva-Pilipich
4. Cytokine network in immunosuppression and tumor development in glioblastoma
Christian Sordo
5. The Double-Edged Role of Interferon Gamma in Cancer Immunity
Segundo Gonzalez
6. Engineering Interleukin-10 for Therapeutic Applications
Pedro Berraondo, Fernando Aranda, Yufei Zheng, Roman Garcia-Fuentes and Aline Risson
7. IL-23 Blockade: A Strategy for Relieving Inflammatory Diseases
Mario García Domínguez
