Full Description
NanoPDT: Nanomaterials-Enhanced Photodynamic Therapy covers extensively the therapeutic potential of multifunctional nanosystems that has made so much progress within the biomedical and pharmaceutical research communities over recent decades. Traditional photodynamic therapy (PDT), however, faces several limitations, primarily due to the hydrophobic nature of photosensitizers (PS), which tend to aggregate in aqueous environments, resulting in inadequate biodistribution and limited bioavailability. These constraints significantly reduce the efficacy of photodynamic therapy. The book also explores the most relevant combination therapies available. Four chapters are dedicated to the combination of NanoPDT with other approaches like Immunotherapy, Radiotherapy, chemotherapy, and photothermal therapy.
NanoPDT: Nanomaterials-Enhanced Photodynamic Therapy is an essential resource for pharmaceutical researchers, clinicians, and students in the fields of nanomedicine, oncology, and photodynamic therapy. It offers a thorough exploration of the latest advancements and future directions, providing valuable insights for those looking to enhance the efficacy and specificity of PDT through nanotechnology and its combined applications. The book's comprehensive coverage of both oncological and non-oncological applications makes it a crucial addition to the literature, bridging the gap between fundamental research and clinical practice.
Contents
1. Introduction to Photodynamic Therapy (PDT)
2. Nanomaterials in PDT (NanoPDT)
3. NanoPDT Classification
4. Metal-Based Nanomaterials in PDT
5. Quantum Dots in PDT
6. Carbon-Based Nanomaterials in PDT
7. Polymer-Based Nanomaterials in PDT
8. Lipid-based Nanomaterials in PDT
9. NanoPDT and Chemotherapy Combination
10. NanoPDT and Photothermal Therapy Combination
11. NanoPDT and Radiotherapy Combination
12. NanoPDT and Immunotherapy Combination
13. Future trends of NanoPDT and regulatory notes