Full Description
Myasthenia Gravis: Disease, Diagnosis and Management is a comprehensive resource that explores recent advancements in diagnosing and treating Myasthenia Gravis, a rare autoimmune disease affecting the neuromuscular junction. With contributions from global experts, this book addresses the increasing prevalence of Myasthenia Gravis, reflecting the latest in diagnostic techniques and novel therapies such as complement inhibitors and FcRn antagonists. It aims to support healthcare professionals in delivering optimal care through evidence-based insights and patient-centered approaches. The book is divided into several chapters, beginning with an overview of the pathogenesis and immunoregulatory defects in Myasthenia Gravis. Subsequent chapters cover diagnostic methods, non-immunosuppressive treatments, and biological therapies targeting the immune system. Key topics include the role of intravenous immunoglobulin (IVIg) and plasma exchange (PLEX) in severe exacerbations, thymectomy, molecular mechanisms, and the potential of hematopoietic stem cell transplants. The book also delves into precision medicine, AI applications, clinical trial considerations, and novel therapeutics like anti-FcRn antibodies. Management strategies for ocular Myasthenia Gravis, and a holistic view of living with the disease are also discussed. Myasthenia Gravis: Disease, Diagnosis and Management is invaluable for healthcare providers, physicians, immunologists, ophthalmologists, rheumatologists, physical therapists, pharmacists, and translators. It offers a modern guide to understanding and managing Myasthenia Gravis, integrating clinical expertise with the latest research to improve patient outcomes.
Contents
1. Introduction to Myasthenia Gravis and Ocular Myasthenia Gravis
2. Diagnosis of Myasthenia Gravis
3. Non-immunosuppressive Treatment of Myasthenia Gravis
4. Biologicals -Monoclonal Antibodies Targeting Immune System for Myasthenia Gravis Treatment
5. Novel Immunotherapies for Myasthenia Gravis
6. Management of Myasthenia Gravis in Severe Exacerbation
7. Role of Thymectomy in Myasthenia Gravis
8. Molecular Mechanisms of Myasthenia Gravis
9. Management of Myasthenia Gravis with Hematopoietic Stem Cell Transplant
10. Precision Medicine in Myasthenia Gravis
11. Application of AI in Management of Myasthenia Gravis
12. Clinical Trial Considerations in Myasthenia Gravis
13. Anti-FcRn Antibodies Based Novel Therapeutics
14. Management of Ocular Myasthenia Gravis
15. Living with Myasthenia Gravis and Future Perspective
