Full Description
Extracellular Vesicle-Based Biovectors for Diagnostic and Biomedical Applications provides comprehensive coverage on not only the biosynthesis, isolation, purification, and functionalization of extracellular vesicles for therapeutic and diagnostic applications, but it also explores the current trends of functionalized extracellular vesicles for biomedical research and for commercial-scale opportunities. Organized into three main parts, the book takes a structured approach. Part I focuses on the fundamental aspects of extracellular vesicles, covering their origin, classification, biosynthesis, isolation techniques, purification challenges, and functionalization for biomedical applications. Part II delves into the therapeutic applications of extracellular vesicles and their role in treating diseases, while also addressing biocompatibility, safety, and translation challenges. , while also addressing biocompatibility, safety, and translation challenges. Part III explores the diagnostic potential of extracellular vesicles in biomedical research, highlighting their role as diagnostic biomarkers in various diseases. It also discusses emerging technologies and the future directions in extracellular vesicle research. Extracellular Vesicle-Based Biovectors for Diagnostic and Biomedical Applications is a valuable reference for researchers and clinicians seeking an in-depth understanding of extracellular vesicles and their potential biomedical applications.
Contents
Part I: Introduction: Extracellular vesicles origin, classifications and biosynthesis, isolation approaches, purification, and functionalization of extracellular vesicles for biomedical applications and new perspectives
1. Introduction to extracellular vesicles: origin, classification, and biosynthesis
2. Isolation, purification, and challenges in extracellular vesicles
3. Characterization of extracellular vesicles: techniques and technologies
4. Drug loading techniques for extracellular vesicles for biomedical applications
5. Functionalization of extracellular vesicles for biomedical applications
Part II: Therapeutic applications of extracellular vesicles
6. Extracellular vesicles in musculoskeletal and cardiovascular applications
7. Extracellular vesicles in neurodegenerative diseases
8. Extracellular vesicles in autoimmune diseases and immunotherapy
9. Extracellular vesicles in diabetes mellitus and metabolic syndrome
10. Extracellular vesicles in cancer therapy
11. Emerging applications of extracellular vesicles in regenerative medicine and tissue engineering
12. Biocompatibility, safety, and challenges in commercial, regulatory, and clinical translation
Part III: Diagnostic applications of extracellular vesicles in biomedical research
13. Extracellular vesicles as diagnostic biomarkers in cancer research
14. Extracellular vesicles in the diagnosis of diabetes mellitus and associated complications
15. Diagnostic application of extracellular vesicles as biomarkers in neurological disorders
16. Prognostic and diagnostic applications of extracellular vesicles in cardiovascular diseases
17. Extracellular vesicles in the diagnosis of autoimmune diseases
18. Emerging technologies and future directions in extracellular vesicle research
