Full Description
Antibiotic Resistance and Nanotherapy is a comprehensive guide that explores an interdisciplinary approach to address the pressing issue of antibiotic resistance and explores the possibility of nanotherapy as a cutting-edge strategy to treat illnesses that are resistant to antibiotics, employing nanoparticles to target and kill bacteria selectively without damaging healthy cells. It details the underlying mechanisms of drug resistance in intracellular and extracellular pathogens and explores the latest advancements in nanotechnology, including the development of innovative nanomaterials and delivery systems that can be utilized to combat antibiotic-resistant infections. This book also discusses the ethical and practical challenges associated with implementing nanotherapy for bacterial resistance. Featuring contributions from experts in the field, this book is an essential resource for researchers, medical professionals, and policymakers seeking to understand and tackle the immediate threat posed by antibiotic resistance.
Contents
1. Introduction to planktonic and biofilm-mediated antimicrobial
resistance and role of nanotechnology in overcoming biofilm-mediated
antibiotic resistance
2. Key determinants of antimicrobial resistance: exploring the influence of
antibiotic pollution on the emergence of multidrug-resistant microbes
3. Drug resistance mechanism in intracellular pathogens and modulation
4. Metal-based nanomedicine against intracellular pathogens
5. Lipid-based nanomedicine against intracellular pathogens
6. Metal-based nanomedicine against extracellular pathogens
7. Polymer-based nanomedicine against extracellular pathogens
8. Lipid-based nanomedicine against extracellular pathogens
9. Interaction between infected host cells and nanodelivery systems
10. Innovative strategies utilizing nanoparticles to disrupt c-di-GMP and
quorum-sensing signaling pathways to combat antibiotic resistance
induced by biofilms
11. CRISPR-Cas systems for antibiotic resistance
12. Synergistic effects of natural compounds and repurposed drugs in
nanotherapy: a strategy to combat biofilm-associated infections
13. Safety, ethical, regulatory issues, and challenges of nanotherapy for
antimicrobial resistance
