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Full Description
Nanotheranostics and Precision Oncology delves into the merging fields of cancer research and nanotechnology, offering a thorough review of the latest advancements in precision oncology. It begins with an exploration of cancer biology, illuminating the genetic foundations of oncogenesis alongside the cellular and molecular mechanisms driving cancer progression, metastasis, and drug resistance. This resistance remains the foremost challenge in cancer care. Across 28 chapters, the book addresses precision medicine's role in overcoming drug resistance, the importance of biomarkers, the interpretation of genetic analyses, and the shift toward personalized oncology.
In addition, the book examines nanotheranostics' applications and mechanisms in cancer diagnosis and treatment, integrating them with precision oncology. It outlines the design, mechanism, and impact of nanoprecision medicine in cancer management. The final section considers the future of nanotheranostics in precision oncology and the challenges of translating these innovations from research to clinical practice. This comprehensive guide serves students, clinicians, researchers, and the pharmaceutical industry involved in nanomedicine, oncology, molecular biology, and precision medicine.
Contents
Section I: Cancer Biology
1. Oncogenesis: Genetic Basis
2. Hallmarks of cancer
3. Cancer Stem Cells and Tumor Microenvironment
4. Mechanisms Underpinning Invasion and Metastasis
5. Drug Resistance and Cancer
Section II: Precision Oncology
6. Introduction to Precision Medicine o of precision medicine's history, components, and milestones.
7. Translational Bioinformatics & Precision Medicine
8. Proteomics, Metabolomics and Precision Medicine
9. Biomarkers and Circulating DNAs as Predictive Molecular Signatures
10. Genomic Strategies for Precision Medicine
11. Immunotherapy as a Tool of Precision Medicine
12. Clinically Approved and Under-Trial Drugs for Precision Oncology
Section III: Nanotheranostics
13. Introduction to Nanotheranostics
14. Active and Passive Targeting of Nanoparticles
15. Nanocontrasts, Nanoprobes, and Nanosensors in Cancer Diagnosis
16. Nanoparticles as Delivery Vehicle for Drugs and Genes
17. Nanoparticles for Thermal Ablation o Exploring novel nanoparticle-mediated cancer therapies.
Section IV: Designing Nanotheranostics for Precision Medicine
18. Current Status of Nanotheranostics in Precision Medicine
19. Nanoimmunotherapy
20. Stimuli Responsive Nanotheranostics for Precision Medicine
21. Pharmacogenomics-Based Nanoprecision Medicine
22. ADME of Nano-Precision Medicines
Section V: Challenges and Future Potentials
23. Challenges in Translation of Nanoprecision Medicine
24. Ethical and Legal Considerations in Use of Nanotheranostic and Precision Medicine
25. Economic Challenges in Use of Nanotheranostics and Precision Medicine
26. Biomarkers That Could be Born Because of Nanotheranostics and Precision Medicine
27. Panomics, Artificial Intelligence, and Precision Medicine
28. Mirage of Nanotheranostics and Precision Medicine: Future Implications