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Full Description
Harnessing Quorum Quenching for Disease Management explores the process of quorum quenching in disrupting bacterial cell communication and how this mechanism can be utilized in the medical field. This book provides a detailed overview of quorum quenching and quorum sensing, delving into the key aspects of this process including the enzymatic mechanisms and methods available to study these. It covers quorum quenching applications, including the regulation of virulence factors, antimicrobial resistance and disease treatment, and the use of quorum quenching bacteria for medical intervention. It also considers genetically modified organisms to produce quorum quenching enzymes, nanomaterials for optimizing quorum quenching, in silico technology and the impact of synthetic biology, closing with a discussion of the current limitations and future prospects for this field. This book is an ideal reference for researchers and advanced students with an interest in quorum quenching and quorum sensing working across a range of fields, including microbiology, cell biology, biomedicine, biochemistry, biotechnology and related areas.
Contents
PART 1: Understanding quorum quenching
1. Quorum sensing and quorum quenching: a brief review
2. Quorum quenching enzymes and inhibitor
3. Methods to study quorum quenching
4. Quorum sensing inhibitors from natural sources
5. Mechanisms of quorum quenching
PART 2: Quorum quenching applications
7. Inhibiting quorum sensing for antimicrobial resistance
8. Inhibiting quorum sensing for disease treatment
9. Genetically modified organisms to produce quorum quenching enzymes
10. Quorum quenching bacteria and their application in the medical field
11. Quorum quenching for biocontrol of plant diseases
PART 3: Quorum quenching: new technologies, limitation and future prospects
12. Nanomaterials for quorum quenching
13. In silico technologies and synthetic biology role in quorum quenching
14. Main limitations and future prospects of quorum quenching strategies