Melanin-Concentrating Hormone : From Metabolism to Sleep Disorders (Molecular Mediators in Health and Disease: How Cells Communicate)

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Melanin-Concentrating Hormone : From Metabolism to Sleep Disorders (Molecular Mediators in Health and Disease: How Cells Communicate)

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  • 製本 Paperback:紙装版/ペーパーバック版／ページ数 480 p.
  • 言語 ENG
  • 商品コード 9780443338007

Full Description

Melanin-Concentrating Hormone: From Metabolism to Sleep Disorders offers a comprehensive understanding of this multifunctional peptide. The book covers a wide range of topics, including molecular biology of MCH, MCH in organ function, pharmacology, and MCH in disease. Recent developments in MCH imaging and pharmacological modulation are explored, as well as the impact of MCH in psychiatric and neurodegenerative disorders, and its role in the neuroimmunological modulation of vitiligo. Additionally, MCH is considered in the context of reproductive behaviour, sleep, cognition and memory, and peripheral function. The book also explores MCH across various species such as humans, reptiles, non-primate mammals and teleosts. Melanin-Concentrating Hormone: From Metabolism to Sleep Disorders is a volume in the "Molecular Mediators in Health and Disease" series and is an ideal reference for researchers working with MCH across the fields of cell biology, molecular biology, pharmacology, neuroscience, endocrinology and beyond.

Contents

Part 1: Introduction to MCH
1. Introduction
2. Melanin-concentrating hormone: a bibliometric perspective

Part 2: Molecular Biology of MCH
3. The Melanin-Concentrating Hormone and its Receptors
4. Genetic and Molecular Aspects of the Melanin-Concentrating Hormone: "From the Gene to the Peptide"
5. MCH Neurons, Neurotransmitters and Co-modulators
6. Synaptic Functions of MCH
7. Non-synaptic mechanisms of MCH communication

Part 3: MCH in Organ Function
8. Energy Homeostasis
9. Reproductive Behavior
10. Sleep
11. Cognition and Memory
12. Peripheral Actions of MCH

Part 4: MCH Pharmacology
13. Development and application of in vivo MCH tracers
14. Agonists and Antagonists

Part 5: MCH in Non-Rodent Biology
15. Mediator in Non-Mammalian Biology: Overview of the Evolutionary Aspects of MCH
16. MCH in Teleosts
17. MCH in Reptiles and Non-Primate Mammals
18. MCH in Humans Part 6: MCH in Disease
19. MCH and Addiction
20. MCH and Psychiatric Disorders
21. MCH and Neurodegenerative Diseases
22. Lactation/Maternal Behavior
23. Mental Disorders/stress-related sleep mood and MCH
24. Measuring circulating MCH in humans and eating disorders