Full Description
Histamines in Neurology and Psychiatry summarizes histamines and their impact on neuroinflammation and brain development in key neural circuits. This book will present the latest research on the physiological regulation of a neuroendocrine responses and releases. This volume will discuss histamine receptor modulators and histamine effects broadly in neurology and psychiatry, and also include clinical applications which will be of interest to practitioners.
Contents
Section 1. Introduction and Neurobiology of Histamines
1. Introduction to Histamines
2. The Histamine Innervations
3. Histamine Receptors (H1-H4): Structure and Signaling Features (New)
4. Histamine Receptors (H1-H4): Distribution in the Brain and Potential Functions
5. Histamine Receptor (H1-H4) Agonists and Antagonists and Their Applications in the CNS
6. Enzymes Involved in Histamine Metabolism (Histidine Decarboxylase, Histamine N-methyltransferase) and Histamine Transporter
7. Histamine-Gated Ion Channels
Section 2. Histamine's Physiological Roles in the Nervous System
8. Histamine's Role in Neurodevelopment
9. Histamine's Role in Sleep-Wake Regulation
10. Histamine's Role in Food Intake
11. Histamine's Role in Memory
12. Histamine in the Crosstalk Between Innate Immune Cells and Neurons
Section 3. Histamine and Neurological Disorders
13. Histamine in Sleep Disorders (e.g., Narcolepsy)
14. Histamine H3 Receptor and Prader-Willi Syndrome
15. Histamine and Cerebral Ischemia
16. Histamine and Cognitive Disorders (e.g., Alzheimer's Disease)
17. Histamine and Neuropathic Pain
18. Histamine and Feeding Disorders
19. Histamine and Movement Disorders (Parkinson's Disease, Huntington's Disease)
20. Histamine and Multiple Sclerosis or Amyotrophic Lateral Sclerosis
21. Histamine and Epilepsy
Section 4. Histamine and Neuropsychiatric Disorders
22. Histamine in Tourette Syndrome and Obsessive-Compulsive Disorder
23. Histamine and Attention Deficit Hyperactivity Disorder
24. Histamine and Schizophrenia
25. Histamine and Alcohol Addiction
26. Histamine and Autism
27. Histamine and Mood Disorders (Anxiety, Depression)
Section 5. Histamine Research Tools for Future Clinical and Experimental Interventions
28. Genetically Encoded Sensors for Measuring Histamine Release in the Brain
29. Optogenetic Intervention of Histamine Receptors
30. Imaging Histamine H3 Receptor with Positron Emission Tomography
31. Imaging Histamine H1 Receptor with Positron Emission Tomography
32. Conclusion
