Full Description
Innovative Nanocarriers for Stimulated Drug Delivery: A Comprehensive Guide to Stimuli-responsive Nanoparticles offers a thorough exploration of the latest developments in nanocarrier technologies that react to various external and internal stimuli. Designed for pharmaceutical professionals and graduate students, this guide provides essential knowledge, spanning from foundational principles to clinical applications. Covering regulatory considerations and experimental techniques, the book equips readers with a deep understanding of the formation, characterization, and use of stimuli-responsive nanoparticles in drug delivery, therapy, and theranostics, making it an invaluable resource for advancing research and practical expertise in this dynamic field.
The book is structured into six distinct parts, with each addressing a critical aspect of stimuli-responsive nanocarriers. It examines external stimuli such as ultrasound and magnetic fields, internal triggers like pH and enzymes, and dual or multimodal systems. Dedicated sections discuss therapeutic applications for cancer and noncancerous diseases, as well as regulatory challenges including toxicity, safety, and clinical translation. Authored by leading experts, the guide serves as a definitive reference for researchers, pharmaceutical scientists, and graduate students, ensuring comprehensive insights into both current achievements and future directions in nanomedicine.
Contents
Part I - Foundations of stimuli-responsive nanocarriers
1. Fundamental of stimuli-responsive materials in drug delivery
2. History, introduction, and physicochemical properties and characterization parameters of stimuli-responsive nanocarriers
Part II - External-responsive nanocarriers for biomedical application
3. Ultrasound-responsive nanocarriers for biomedical application
4. Thermal-responsive nanocarriers for biomedical application
5. Magnetic-responsive nanocarriers for biomedical application
6. Light-sensitive nanocarriers for biomedical application
7. Electric field-response systems for biomedical application
Part III - Internal stimuli-responsive nanocarriers for biomedical application
8. pH-responsive nanocarriers for biomedical application
9. Hypoxia-responsive nanocarriers for biomedical application
10. Redox-responsive nanocarriers for biomedical application
11. Enzyme-responsive nanocarriers for biomedical application
12. Glucose-responsive nanocarriers for biomedical application
13. microRNA responsive nanocarriers for biomedical application
Part IV - Dual and multimodal-responsive nanocarriers for biomedical application
14. Temperature and pH dual-stimuli-responsive nanocarriers for biomedical application
15. pH and redox potential dual-stimuli-responsive nanocarriers for biomedical application
16. Dual-stimuli-responsive nanocarriers for biomedical application
17. Stimuli-responsive charge-reversal nanocarriers for biomedical application
18. Stimuli-responsive nanocarriers for image-guided therapy
Part V - Therapeutic aspects of stimuli-responsive nanocarriers
19. Metallic stimuli-responsive nanocarriers in the treatment of various cancer
20. Non-metallic stimuli-responsive nanocarriers in the treatment of various cancer
21. Metallic stimuli-responsive nanocarriers in the treatment of noncancerous disease
22. Non-metallic stimuli-responsive nanocarriers in the treatment of noncancerous disease
Part VI - Recent advances and regulatory aspects of stimuli-responsive nanocarriers
23. Clinical translation, challenges, biological toxicity and safety issues associated with stimuli-responsive nanocarriers
24. Recent updates on clinical trials associated with stimuli-responsive nanocarriers
25. Limitations, hurdles conclusion and future prospective of stimuli-responsive nanocarriers
