Innovative Nanocarriers for Stimulated Drug Delivery : A Comprehensive Guide to Stimuli-responsive Nanoparticles

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Innovative Nanocarriers for Stimulated Drug Delivery : A Comprehensive Guide to Stimuli-responsive Nanoparticles

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  • 製本 Paperback:紙装版/ペーパーバック版/ページ数 550 p.
  • 言語 ENG
  • 商品コード 9780443336416

Full Description

Innovative Nanocarriers for Stimulated Drug Delivery is a comprehensive guide that summarizes the recent advances and achievements in nanocarriers that are responsive to external or internal stimuli. The book presents different stimuli-sensitive strategies and their applications in drug delivery, therapy, and theranostics. Intended for pharmaceutical researchers in both academia and corporate settings, and graduate students the coverage spans from the foundational aspects of these particles all the way to regulation and clinical trials. The book is organized into six parts. Part I provides the foundation of stimuli-responsive nanocarriers, including fundamental knowledge on the experiential and experimental aspects of stimuli-responsive nanocarriers. Part II discusses external-responsive nanocarriers for biomedical applications, such as ultrasound, thermal, magnetic, light, and electric field-response systems. Part III describes internal stimuli-responsive nanocarriers for biomedical applications, including pH, hypoxia, redox potential, enzyme, glucose, and microRNA-responsive nanocarriers. Part IV covers dual and multimodal-responsive nanocarriers, while Part V discusses therapeutic aspects of stimuli-responsive nanocarriers, such as metallic and non-metallic stimuli-responsive nanocarriers in the treatment of various cancer and noncancerous diseases. Finally, Part VI provides recent advances and regulatory aspects of stimuli-responsive nanocarriers, including clinical translation, challenges, biological toxicity, safety issues, clinical trials, and future perspectives. Innovative Nanocarriers for Stimulated Drug Delivery is a complete reference, providing an understanding of the principles behind formation, characterization, applications, regulations, toxicity, challenges, and future perspectives of stimuli-responsive nanomedicine. The book is written by established worldwide experts, ensuring that the content of this book meets the needs of the audience. This book is an essential reference for anyone interested in the field of stimuli-responsive nanocarriers, including researchers and scientists in pharmaceutical industries as well as graduate students in related fields.

Contents

Part I - Foundations of stimuli-responsive nanocarriers
1. Fundamental of stimuli-responsive materials in drug delivery
2. History, introduction, and physicochemical properties and characterization parameters of stimuli-responsive nanocarriers

Part II - External-responsive nanocarriers for biomedical application
3. Ultrasound-responsive nanocarriers for biomedical application
4. Thermal-responsive nanocarriers for biomedical application
5. Magnetic-responsive nanocarriers for biomedical application
6. Light-sensitive nanocarriers for biomedical application
7. Electric field-response systems for biomedical application

Part III - Internal stimuli-responsive nanocarriers for biomedical application
8. pH-responsive nanocarriers for biomedical application
9. Hypoxia-responsive nanocarriers for biomedical application
10. Redox-responsive nanocarriers for biomedical application
11. Enzyme-responsive nanocarriers for biomedical application
12. Glucose-responsive nanocarriers for biomedical application
13. microRNA responsive nanocarriers for biomedical application

Part IV - Dual and multimodal-responsive nanocarriers for biomedical application
14. Temperature and pH dual-stimuli-responsive nanocarriers for biomedical application
15. pH and redox potential dual-stimuli-responsive nanocarriers for biomedical application
16. Dual-stimuli-responsive nanocarriers for biomedical application
17. Stimuli-responsive charge-reversal nanocarriers for biomedical application
18. Stimuli-responsive nanocarriers for image-guided therapy

Part V - Therapeutic aspects of stimuli-responsive nanocarriers
19. Metallic stimuli-responsive nanocarriers in the treatment of various cancer
20. Non-metallic stimuli-responsive nanocarriers in the treatment of various cancer
21. Metallic stimuli-responsive nanocarriers in the treatment of noncancerous disease
22. Non-metallic stimuli-responsive nanocarriers in the treatment of noncancerous disease

Part VI - Recent advances and regulatory aspects of stimuli-responsive nanocarriers
23. Clinical translation, challenges, biological toxicity and safety issues associated with stimuli-responsive nanocarriers
24. Recent updates on clinical trials associated with stimuli-responsive nanocarriers
25. Limitations, hurdles conclusion and future prospective of stimuli-responsive nanocarriers

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