Full Description
Innovative Nanocarriers for Stimulated Drug Delivery: A Comprehensive Guide to Stimuli-responsive Nanoparticles summarizes recent advances and achievements in nanocarriers responsive to external or internal stimuli. The book presents different stimuli-sensitive strategies and their applications in drug delivery, therapy, and theranostics. Sections provide fundamental knowledge on the experiential and experimental aspects of stimuli-responsive nanocarriers, discuss external-responsive nanocarriers for biomedical applications, such as ultrasound, thermal, magnetic, light, and electric field-response systems, and describe internal stimuli-responsive nanocarriers for biomedical applications, including pH, hypoxia, redox potential, enzyme, glucose, and microRNA-responsive nanocarriers.
Additionally, the book covers dual and multimodal-responsive nanocarriers and the therapeutic aspects of stimuli-responsive nanocarriers, such as metallic and non-metallic stimuli-responsive nanocarriers in the treatment of various cancer and noncancerous diseases. Finally, recent advances and regulatory aspects of stimuli-responsive nanocarriers, including clinical translation, challenges, biological toxicity, safety issues, clinical trials, and future perspectives are covered.
Contents
Part I - Foundations of stimuli-responsive nanocarriers
1. Fundamental of stimuli-responsive materials in drug delivery
2. History, introduction, and physicochemical properties and characterization parameters of stimuli-responsive nanocarriers
Part II - External-responsive nanocarriers for biomedical application
3. Ultrasound-responsive nanocarriers for biomedical application
4. Thermal-responsive nanocarriers for biomedical application
5. Magnetic-responsive nanocarriers for biomedical application
6. Light-sensitive nanocarriers for biomedical application
7. Electric field-response systems for biomedical application
Part III - Internal stimuli-responsive nanocarriers for biomedical application
8. pH-responsive nanocarriers for biomedical application
9. Hypoxia-responsive nanocarriers for biomedical application
10. Redox-responsive nanocarriers for biomedical application
11. Enzyme-responsive nanocarriers for biomedical application
12. Glucose-responsive nanocarriers for biomedical application
13. microRNA responsive nanocarriers for biomedical application
Part IV - Dual and multimodal-responsive nanocarriers for biomedical application
14. Temperature and pH dual-stimuli-responsive nanocarriers for biomedical application
15. pH and redox potential dual-stimuli-responsive nanocarriers for biomedical application
16. Dual-stimuli-responsive nanocarriers for biomedical application
17. Stimuli-responsive charge-reversal nanocarriers for biomedical application
18. Stimuli-responsive nanocarriers for image-guided therapy
Part V - Therapeutic aspects of stimuli-responsive nanocarriers
19. Metallic stimuli-responsive nanocarriers in the treatment of various cancer
20. Non-metallic stimuli-responsive nanocarriers in the treatment of various cancer
21. Metallic stimuli-responsive nanocarriers in the treatment of noncancerous disease
22. Non-metallic stimuli-responsive nanocarriers in the treatment of noncancerous disease
Part VI - Recent advances and regulatory aspects of stimuli-responsive nanocarriers
23. Clinical translation, challenges, biological toxicity and safety issues associated with stimuli-responsive nanocarriers
24. Recent updates on clinical trials associated with stimuli-responsive nanocarriers
25. Limitations, hurdles conclusion and future prospective of stimuli-responsive nanocarriers
