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Full Description
Emerging Paradigms in Delivery of Therapeutic Agents for the Treatment of Glioblastoma describes the intense research and clinical developments that are required to optimize the available treatment options and the potential side effects to heal brain cancer. The success of this strategy includes the use of validated biomarkers, appropriate patient selection criteria, strategies to prevent adverse events, and the implementation of immunotherapy in multimodal treatment approach. In 18 chapters, this title sets forth the rationales for promising therapies like immunotherapy, including immune checkpoint blockade, chimeric antigen receptor T (CAR T) cell therapy, oncolytic virotherapy, and vaccine therapy.
In addition, the book reviews potential novel agents, the current status of preclinical and clinical trials, and the challenges and future perspectives in glioblastoma immuno-oncology. This book is a valuable resource for health professionals, scientists and researchers, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.
Contents
1. Glioblastoma: Overview of the pathogenesis, clinical features, and diagnosis
2. The challenges of brain tumour therapeutics, the future of brain tumour nanotherapeutics
3. Role of Various Therapeutic Targets for in treatment of Glioblastoma
4. Nanocarrier-Mediated Approaches and Conventional Therapies for Treatment Glioblastoma
5. siRNA and miRNA-based strategies for management of Glioblastoma
6. Lipid based nanocarrier(s) as Delivery Vehicles for Brain Tumour Therapy
7. Polymeric Nanoparticulate Carrier for Brain Tumour Therapy
8. Convection-Enhanced Delivery for Treatment of Glioblastoma
9. Herbal approaches for treatment of glioblastoma
10. Nanomedicine based photodynamic therapy for glioblastoma
11. Thermoresponsive nanocarrier(s) based therapy for glioblastoma
12. Peptide anchored nanocarrier(s) therapy for glioblastoma
13. Theranostic applications of lipid-polymer based nanocarrier(s) for treatment of glioblastoma
14. Targeting strategies in Gene Therapy for Glioblastoma
15. Nanocarrier-based combination therapy for the treatment of glioblastoma
16. Dendrimer assisted nanotechnological ways for glioblastoma drug delivery
17. Inorganic/metallic nanoparticles in the treatment of glioblastoma
18. Graphene Quantum Dots based Therapy for Glioblastoma