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Full Description
Plant-Based Drug Discovery: Unveiling Molecular Targets for Metabolic Conditions provides an in-depth examination of the molecular mechanisms of phytochemicals and their potential in treating metabolic diseases. This comprehensive guide begins with an introduction to the prevalence and impact of metabolic disorders, emphasizing the significant role of phytochemicals in their management. The book delves into scientific concepts and research findings, offering valuable insights for researchers and healthcare professionals in the fields of molecular biology, biochemistry, pharmacology, and biotechnology. Chapters cover various crucial topics such as oxidative stress, epigenetic mechanisms, and mitophagy.
In addition, they explore the targeting of molecular chaperones and the molecular targets of plant nutraceuticals for treating obesity, cardiovascular disease, and type 2 diabetes. The book also addresses technological advances, including AI and nanotechnology, highlighting opportunities and challenges in improving the use of plant molecules for metabolic disorder treatments. It serves as an essential resource for those engaged in drug discovery and related areas.
Contents
Section 1: Introduction
1. Overview of human metabolic diseases associated with lifestyle
Section 2: Phytochemicals and molecular targets
2. Significance of phytochemicals in metabolic disorders
3. Molecular connection of oxidative stress and metabolic syndrome: Therapeutic role of phytocomponents
4. Epigenetic mechanisms of phytochemicals in cure of metabolic diseases
5. Plant‑derived bioactive peptides for treatment of metabolic disorders
6. Efficiency of phytochemicals to cure metabolic diseases by targeting mitophagy
7. Phytochemicals as promising therapeutic approaches for inflammasome-related metabolic diseases
8. Regulatory impact of phytochemicals on metabolic diseases by targeting Nrf2-ARE signaling mechanism
9. Targeting molecular chaperones with phytochemicals for drug discovery in metabolic ailments
10. Molecular targets of plant nutraceuticals against obesity
11. Molecular insight to cure cardiovascular diseases through plants compounds
12. Mechanistic insights of important medicinal plant compounds in managing type 2 diabetes mellitus
Section 3: Nanotechnology methods
13. Attenuation of hyperlipidemia by medicinal plants with nanotechnological methods
Section 4: Clinical study
14. Clinical evidences of phytochemicals in cure of metabolic diseases
Section 5: Technologies and challenges for plant-based drug discovery
15. Artificial intelligence in plant-based drug discovery against metabolic disorders
16. Integration of high-throughput omics technologies in discovery of phytodrugs to treat metabolic diseases
17. Multi-targets drug design for screening of phytochemicals to cure of metabolic disorders
18. New opportunities and challenges for improving the druggability of plant product against metabolic disorders
