Full Description
Role of Gut Microbiome in Neurodegenerative Disorders provides an overview of the gut microbiota and its interactions with the gut and the central nervous system. This book reviews the relevance of this axis to the pathogenesis of neurodegenerative diseases, such as Parkinson's disease (PD), Alzheimer's disease (AD), and Multiple sclerosis (MS). Various chapters discuss the effects of gut derived particles in various parts of brain and the targeting pathways leading to protein deposition in brain.
Contents
1. Overview of Neurodegenerative Disorders
2. Gut Microbiota and Neurological Diseases
3. Gut-Brain Axis
4. Gut-Brain Axis in Neurological Diseases
5. Difference in the constitution of Gut Microbiota during Neurodegenerative Disorders
6. Gut Metabolites in Neurodegenerative Diseases
7. Influence of Gut Microbiota on Cerebellum
8. Influence of Gut Microbiota on Hippocampus
9. Influence of Gut Microbiota on Axonal Cells of the brain
10. Mechanistic action of Gut Microbiota on Glial cells
11. Gut as a second brain- Largest producer of serotonin
12. Gradual Shift of gut microbial Population as a diagnostic marker for Neurodegenerative disorders
13. Gut metabolites - effective biomarker for Neurodegenerative disorder
14. Protocol - Isolation of Gut Microbiome from Faecal sample
15. Gut metabolites isolation from Blood
16. Metagenomics and sequence analysis
17. Computer aided detection method
18. Existing therapeutic options to alter gut composition in Neurodegenerative Disorders
19. Dietary and Gut microbiome
20. Ongoing clinical trials
21. Ethical hurdles for the treatment of a disease focusing Gut Microbiota
22. Futuristic therapies in pipeline for the betterment of Neurodegenerative Disorders
