Fundamentals of Brain Organoids for Neurological Diseases

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Fundamentals of Brain Organoids for Neurological Diseases

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  • 製本 Paperback:紙装版/ペーパーバック版/ページ数 400 p.
  • 言語 ENG
  • 商品コード 9780443298981

Full Description

Fundamentals of Brain Organoids for Neurological Diseases provides a practical resource for researchers on how to utilize and apply brain organoids. This book is organized into nine distinct sections, guiding the reader through each step from advanced overview of what organoids are to the use of brain organoids in various neurodevelopmental disorders and neurodegenerative diseases. In later sections, this book reviews the necessary methods involved in organoid development including the elements and challenges involved. This book will serve as a valuable tool for researchers, helping to advance the understanding of brain biology and disease mechanisms.

Researchers use brain organoids to study the formation of neural tissues, investigate the processes involved in brain development, and gain a better understanding of neurological disorders and diseases. Brain organoids are particularly useful in studying developmental disorders, neurodegenerative diseases, and infectious diseases that affect the brain.

Contents

Section I An overview about Organoids
1. An overview on organoids - Past, Present and Future scenario of organoids

Section II Neurodevelopmental disorder
2. A brief introduction about Neurodevelopmental disorders
3. Use of brain organoids for Autism
4. Role of brain organoids in Rett Syndrome
5. Role of brain organoids in Bipolar disorder
6. Ongoing clinical trials on use of Brain organoids for neurodevelopmental disorders

Section III Neurodegenerative diseases
7. An overview of Neurodegenerative diseases
8. Use of brain organoids for Parkinson's disease (PD) and Alzheimer's disease (AD)
9. Application of brain organoids in Huntington's disease (HD)
10. Ongoing clinical trials on use of Brain organoids for neurodegenerative diseases (AD, PD, HD)

Section IV Methods involved in organoids development
11. How HiPSCs are derived into organoids
12. Elements required and days involved in organoid generation

Section V - Application and advancement of Brain organoids
13. Brain organoids - Challenges while constructing organoids
14. Existing drug targeting and research using Brain organoids

Section VI - Ethical consideration while conducting organoids research
15. Ethical consideration while conducting organoids research

Section VII - Future Direction and Conclusion
16. Future Direction & Conclusion

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