Full Description
Extracellular Mitochondria in Health and Disease covers this new and significant area of research, shedding light on their roles in intercellular communication and disease pathology. These tiny powerhouses, traditionally known for their intracellular functions, are now recognized for their extracellular activities that impact various physiological and pathological processes. The book delves into a range of topics, including cellular mechanisms of mitochondrial transfer, metabolic signaling, and the crosstalk between extracellular vesicles and mitochondria. It serves as a comprehensive guide for scientists, researchers, and students eager to explore these novel findings and their potential implications.
Other sections examine the roles of extracellular mitochondria in immune regulation and inflammation, neurodegeneration and neuroprotection, and their therapeutic potential. By bridging gaps in existing literature, this resource offers up-to-date research and discoveries, providing valuable insights into how extracellular mitochondria could revolutionize medical advancements and improve patient outcomes.
Contents
Chapter 1. General introduction
Marvin Edeas
Chapter 2. Cellular mechanisms of mitochondrial transfer and metabolic
signaling
Beatriz Guedes, Inês Melo-Marques, Ana Raquel Esteves and Sandra Morais Cardoso
Chapter 3. Modern techniques for studying extracellular mitochondria
Pasquale D'Acunzo, Efrat Levy and Carla Lopes
Chapter 4. Interplay between extracellular vesicles and mitochondria
Patricia Coelho and Paulo Pinheiro
Chapter 5. Extracellular mitochondria: dual roles in neurodegeneration and neuroprotection
Tomas Ferro, Adrián Tejero and Filipe Duarte
Chapter 6. Extracellular vesicles bearing mitochondria in cardiometabolic diseases
M. Carmen Martinez and Ramaroson Andriantsitohaina Ramaroson
Chapter 7. Therapeutic potential of extracellular mitochondria: applications and challenges
Cristina Mas-Bargues, Javier Huete-Acevedo, Marta Arnal-Forné, Sandra Atencia-Rabadán, José de Santiago-Montesinos, Karolina Dorosz and Consuelo Borrás
Chapter 8. Conclusions and future perspectives
Carla Lopes
