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Full Description
Advanced Techniques in Antibody Generation: Antibody Engineering, Hybridoma Technology, and Phage Display offers a detailed overview of the latest techniques and protocols available in antibody engineering, providing a basis for developing novel and enhanced antibody-based therapeutics for various illnesses and conditions. Early chapters focus on mechanisms and purposes of antibody production across different hosts and the structure and function of immunoglobulin molecules. The book then covers a range of aspects of antibody engineering, including antibody synthesis and screening, antibody engineering and optimization, production, and utilization.
The book provides in-depth explanations of antibody engineering approaches, including phage display, hybridoma, and recombinant DNA technologies. Therapeutic, diagnostic, and biotechnological applications are also covered, providing readers with a comprehensive understanding of the methodologies discussed, and thus empowering them to effectively utilize these techniques in their own research or development initiatives.
Contents
1. Antibody engineering recent advances: From discovery to clinical applications
2. Mechanisms and purposes of immunogen-induced antibody production in different hosts
3. Methods and applications for antibody screening and optimization
4. Immunoglobulin molecules: Structure, function, and applications
5. Therapeutic and diagnostic applications of antibody-based strategies for precision medicine
6. Targeted drug delivery using antibodies: Concepts, methods, and applications
7. Hybridoma, monoclonal antibody technology
8. Optimizing therapeutic antibodies through glyco-engineering
9. Applications of hybridoma-based monoclonal antibodies in therapeutics research and diagnostics
10. Engineering and applications of bispecific and multi-specific antibodies
11. Hybridoma technology in the biotechnology industry: Current status and future trends
12. Bacteriophage display technology or phage display technology
13. Antibody engineering using phage display, yeast display and ribosome display
14. Phage display in cancer research and vaccine development
15. Diagnostic and therapeutic applications of phage display
16. Phage display technology in the biotechnology industry: Current status and future trends directions
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