Retinoic Acids in Cancer Therapy : Mechanisms of Sensitivity, Resistance, and Methods of Delivery (Cancer Sensitizing Agents for Chemotherapy)

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Retinoic Acids in Cancer Therapy : Mechanisms of Sensitivity, Resistance, and Methods of Delivery (Cancer Sensitizing Agents for Chemotherapy)

Ghavami, Saeid (EDT)/ Zarrabi, Ali (EDT)/ Cordani, Marco (EDT)

ウェブストア価格 ¥37,452（本体¥34,048）
Academic Press Inc（2026/03発売）
外貨定価 US$ 175.00
ポイント 340pt

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製本 Hardcover:ハードカバー版／ページ数 216 p.
言語 ENG
商品コード 9780443223051

Full Description

Retinoic Acids in Cancer Therapy: Mechanisms of Sensitivity, Resistance, and Methods of Delivery, Volume 21 offers a detailed exploration of how All Trans Retinoic Acid (ATRA) functions to kill cancer cells, as well as the survival mechanisms of certain cells when treated with this drug. This comprehensive book delves into the specific cell pathways and compartments that are involved in the action of retinoic acids (RAs) in inhibiting cell proliferation across various cancers, providing invaluable insights for continued research and improved therapeutic approaches in oncology.

The book comprises 16 chapters that address the molecular structure and biological properties of ATRA, elucidate the mechanisms of resistance to ATRA, and evaluate its efficiency in treating seven different cancers. Additionally, it discusses strategies to enhance ATRA cancer treatment and offers future perspectives on its applications. As a vital resource for health professionals, researchers, and students alike, this volume aims to expand the collective understanding of ATRA's therapeutic potential and inspire the development of new, more effective cancer treatments.

1. Molecular structure and biological properties of ATRA
2. Cellular and molecular determinants of all-trans retinoic acid sensitivity in different cancers
3. Mechanisms of resistance to ATRA
4. Efficiency of All-Trans Retinoic Acid on Gastric Cancer
5. Efficiency of All-Trans Retinoic Acid on glioblastoma
6. Efficiency of All-Trans Retinoic Acid on lung cancer
7. Efficiency of All-Trans Retinoic Acid on breast cancer
8. Efficiency of All-Trans Retinoic Acid on liver cancer
9. Efficiency of All-Trans Retinoic Acid on stomach cancer
10. Efficiency of All-Trans Retinoic Acid on colon cancer
11. Bioengineered models for investigating ATRA anticancer efficacy and biocompatibility
12. Delivery methods for ATRA
13. Apoptosis, autophagy, and UPR and its impact in ATRA-induced toxicity in cancer cells.
14. ATRA and Cancer Stem Cell Biology
15. OMICs strategies to Improve the ATRA Cancer Treatment
16. Future Perspectives in ATRA applications in Cancer Biology and Nano technology