Full Description
The Scientific Basis of Monkeypox: Features, Prevention, and Treatments advances understanding of monkeypox and provides a framework for future research with evidence-based and forward-looking content. Content makes use of modeling systems and current experiences derived from case studies to provide material that is cross-disciplinary, bridging interdisciplinary divides. Furthermore, consideration is given to the behavioral response to monkeypox infection, including barriers to vaccination. Each chapter contains structured content, including policy and procedures, applications to new or emerging communicable diseases, a mini dictionary of terms, and summary points.
Chapter contributions are from leading national and international specialists, including those from world renowned institutions who provide a global perspective. The book is a perfect reference for specialists in infectious diseases, virologists, microbiologists, health scientists, public health workers, doctors, pharmacologists, and research scientists.
Contents
Preface
Section 1: Setting the Scene and Introductory Chapters
1. A synopsis of mpox
2. Monkeypox unveiled: understanding its impact on public health
3. Human mpox (monkeypox) virus and its evolution
4. Importance of emerging lineages of mpox (monkeypox) virus: an updated narrative
5. Bridging borders: the collective fight against monkeypox outbreaks
6. Social media and the response to mpox (monkeypox)
Section 2: The Biology And Transmission Of mpox (monkeypox)
7. Monkeypox virus: fundamental features of its particle, replication cycle, cytopathic effects and research models
8. Biology of the mpox virus and the cysteine protease structures and basis of in silico studies
9. The serial interval distributions of the mpox virus infection
10. Investigating mpox: linking web tools and genomic analysis
11. Mathematical Modelling of Mpox: A Review
Section 3: Detection And Confirmation
12. Development, validation, and use of assays within the clinical diagnostic and Emergency Use Authorization/Food and Drug Administration (EUA/FDA) contexts
13. Primers and Probes for the Diagnostics of mpox (monkeypox) Virus
14. Monkeypox and wastewater surveillance: tracing the spread of a viral outbreak through environmental monitoring
Section 4: Effects On the Body. Tissues And Organs Systems
15. Time related change in skin lesions and their progression
16. Atypical skin manifestations of mpox
17. Variations in clinical features and symptoms in mpox (monkeypox) infection: fever and beyond
18. Otolaryngological features of mpox: lymphadenopathy, pharyngeal and airways
19. Cardiac involvement of mpox (monkeypox)
Section 5: Vaccinations, Treatments And Alleviation Of Symptomology
20. The psychological responses of mpox (monkeypox) virus vaccination in health care workers: international aspects
21. Immunoinformatics and mpox (monkeypox) virus vaccines
22. Barriers to mass vaccination against monkeypox: an overview
23. Approved and experimental antivirals for mpox
24. Repurposing drugs for monkeypox using artificial intelligence
25. Monkey Pox clinical management-A Review
26. Treating pustular skin lesions in viral infection: mpox and beyond
27. Treating concomitant HIV and mpox virus infection
Section 6: Case Studies
28. Case Study: Mpox (monkeypox) and a typical scenario of clinical presentation, diagnosis and successful treatment
29. Case Study: Heterosexual transmission of mpox
30. Case Report: Simultaneous presentation of human monkeypox virus and sexually transmited diseases (STDs): a diagnostic and management challenge
31. Case study: Anatomopathological findings in different mpox cutaneous lesions
32. Case Study: Scaring and quality of life in mpox
Section 7: Resources
33. Resources for the study and investigation of mpox (monkeypox)
