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Full Description
Advances in gastrointestinal cancer therapy: Spotlight on nanoarchitectures considers applications of nanostructures in treatment of gastrointestinal tumors and their capacity in improving efficacy of therapeutics, The book has a strong focus on overcoming challenges in gastrointestinal cancer therapies such as drug resistance, introduction of nanomedicine for drug and gene delivery, and new insight for clinical trials in treatment of patients with gastrointestinal tumors. In 25 chapters Advances in gastrointestinal cancer therapy: Spotlight on nanoarchitectures describes the multiple problems in treatment of gastrointestinal cancers including drug resistance, radio-resistance, inability to reaching to tumor site, degradation of genetic tools by RNase enzymes, and acidic pH of tumor microenvironment that may negatively affect efficacy of chemotherapeutic agents by making changes in their structure. This book is a valuable resource for Students, researchers and academicians in oncology and medical engineering.
Contents
Section I: Nanomedicine and cancer 1. Cancer therapy challenges 2. Development of therapy resistance in cancer 3. An overview of oncogenic and onco-suppressor pathways in cancer 4. Role of nanomedicine in cancer therapy: Promising and opportunities 5. Optimization, design and development of nanostructures for purpose of cancer therapy: Principles of cargo loading and exploring new emerging platforms Section II: Gastrointestinal tumors: Pathogenesis and progression 6. Gastric cancer: Epidemiology, pathogenesis and progression factors 7: Liver cancer: Epidemiology, pathogenesis and progression factors 8. Colorectal cancer: Epidemiology, pathogenesis and progression factors 9. Pancreatic cancer: Epidemiology, pathogenesis and progression factors 10. Esophageal cancer: Epidemiology, pathogenesis and progression factors Section III: Nanomedicine and gastric cancer 11. Polymeric nanoparticles in gastric cancer therapy 12. Lipid-based nanoparticles in gastric cancer therapy 13. Carbon-based nanoparticles in gastric cancer therapy 14. Metal-based nanoparticles in gastric cancer therapy Section IV: Nanomedicine and liver cancer 15. Polymeric nanoparticles in liver cancer therapy 16. Lipid-based nanoparticles in liver cancer therapy 17. Carbon-based nanoparticles in liver cancer therapy 18. Metal-based nanoparticles in liver cancer therapy Section V: Nanomedicine and Colorectal cancer Chapter 18: Polymeric nanoparticles in gastric cancer therapy 19. Lipid-based nanoparticles in gastric cancer therapy 20. Carbon-based nanoparticles in gastric cancer therapy Chapter 21: Metal-based nanoparticles in gastric cancer therapy Section VI: Nanomedicine and pancreatic cancer 21. Polymeric nanoparticles in gastric cancer therapy 22. Lipid-based nanoparticles in gastric cancer therapy 23. Carbon-based nanoparticles in gastric cancer therapy 24. Metal-based nanoparticles in gastric cancer therapy Chapter VII: Nanomedicine and esophageal cancer 25. An overview of nanostructures in esophageal cancer therapy
