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Full Description
Isotopically-Labeled Compounds: Recent Advances and Emerging Topics in Synthesis and Applications delves into the transformative developments in isotopic labelling, a crucial field underpinning advancements in chemistry, biology, and medicine. The book emphasizes innovative methodologies for synthesizing compounds labelled with isotopes such as tritium, carbon-14, and various stable isotopes. It also discusses the tools and technologies refined over recent years to enhance analytical precision in their study. By combining theory with practical applications, it serves as an invaluable resource for researchers and professionals seeking deeper insights into isotopic synthesis and utilization.
Additionally, the book explores emerging topics, including novel applications in drug development, environmental tracing, and biochemical research. It integrates findings that push the boundaries of isotopic analysis, offering perspectives on future trends and challenges in the field.
Contents
1. Introduction
2. Recent advances in deuterium and tritium chemistry
3. Carbon-14 and tritium radiolabeling of protein derivatives
4. PET and SPECT isotopes: Basic radiochemistry, new trends, and applications in molecular imaging
5. Recent developments for the synthesis of stable isotopically labeled compounds
6. Preclinical and clinical studies of pharmaceuticals supported by labeled compounds
7. Labeled compounds in agrochemical applications
8. Emerging fields in the chemistry of isotopes and their applications
9. Deuterated active pharmaceutical ingredients
10. Green and sustainable approaches to isotope labeling
