Full Description
Lifestyle Epigenomics, a new volume in the Translational Epigenetics series, comprehensively details the interplay between lifestyle factors and epigenetic modifications associated with the onset of noncommunicable diseases and aging, shedding light on potential preventive and therapeutic strategies for disease from an epigenomics perspective. Here, more than 35 international experts in the field consider how lifestyle choices or habits can condition or prevent disease, along with tools for new research, from bioinformatics methodology to non-invasive sampling.
Early, foundational chapters are followed by all-inclusive sections on epigenetic machinery in health and disease; dietary factors and epigenetics; adiposity and physical activity and epigenetics; psychological stress, social environment, toxins and contaminants exposure effects on epigenetics; and transgenerational and childhood epigenetics. To support understanding, each chapter includes a summary and key points lists, terms and definition, as well as research case studies outlining core components of recent studies, detailing their conditions, research techniques involved, and outcomes.
Contents
SECTION I: Introduction
1. Introduction to lifestyle-relate epigenetic changes in disease aetiology
2. Lifestyle factors in aging and non-communicable disease
SECTION II: Epigenetic machinery in health and disease
3. Epigenetic regulation in health and disease
4. Epitranscriptomics in health and diseases
5. Sirtuins in health and diseases.
6. Epigenetic mechanisms and exosomes in the effect of lifestyle factors on health
7. Epigenetic Clock and leukocyte telomere Length
8. Mitochondrial DNA Methylation and Human Diseases
9. Gut Microbiota and epigenetic mechanisms
10. Bioinformatics tools to study epigenetic mechanisms and lifestyle
11. Liquid Biopsy and epigenetic biomarkers for evaluation lifestyle factors effects on health
12. Current perspectives on possible Epigenetic therapy
SECTION II: Dietary factors and epigenetics
13. Healthy diets and epigenetic regulation
14. Vitamin D and vitamin B12 and epigenetic mechanisms in health a disease
15. NNMT and epigenetic mechanisms in health and disease
16. Dietary phytochemicals and epigenetic mechanisms in health and disease
17. Energy restriction and ketogenic diets
18. Diet, gut microbiota and epigenetics interplaying in health and disease
SECTION III: Adiposity and Physical activity and epigenetics
19. Obesity and epigenetics. Matthias Blüher
20. Impact of physical exercise on epigenetics and metabolic disorders
21. Physical activity, epigenetics and longevity
22. Epigenetics impact of exercise on cognitive impairment and memory
23. Physical activity and epigenetic regulation in depression
24. Exercise and epigenetic regulation in cancer survivors
SECTION IV: Psychological stress, social environment, toxics and contaminants exposure effect on epigenetics
25. Alcohol abuse and epigenetic regulation of human health
26. Drug abuse and epigenetic regulation of human health
27. Air pollution and epigenetic regulation of human health
28. Endocrine disruptors and epigenetic regulation of human health
29. Micro(nano)plastics and epigenetic regulation of human health
30. Epigenetic changes induced by stress exposure and metabolic diseases
31. Social adversity and epigenomics
SECTION V: Transgenerational and childhood epigenetics
32. Father lifestyle and offspring's epigenetic regulation
33. Mother lifestyle and offspring's epigenetic regulation
34. Breastfeeding and epigenetic regulation of human health
35. Childhood lifestyle and epigenetic regulation of human health
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