Full Description
Neuroglia in the Healthy Nervous System, Part I provides insights into newly emerging developments in neuroglia biology, focusing on the healthy nervous system. Driven by advances in genetics, transcriptomics, electrophysiological, and imaging techniques, this volume bridges the gap between neuroglia basic science and neuroglia clinical research. The book provides an overview of neuroglia biology, highlighting emerging technologies used to unravel the role of neuroglial cells in specific brain functions. The book also discusses strategies using neuroglia as a therapeutic target.
Contents
1. Neuroglia in the healthy brain: An introduction
2. Evolution of neuroglia: from worm to man
3. Orchestrating the glial compartment: ontogeny and developmental interaction of astrocytes, oligodendrocytes, and microglia
4. Glia and aging (rodent/human)
5. Physiology of neuroglia of the central nervous system
6. Gliotransmission in physiological and pathological conditions
7. Glia and brain energy metabolism
8. Neuroglia and the blood-brain barrier
9. Metabolic control of microglia in health and disease
10. The glymphatic system
11. Glia and brain-gut axis (rodent/human)
12. Glia and extracellular matrix molecules
13. In vitro models for human neuroglia
14. Animal-based approaches to understanding glia physiology in vitro and in vivo
15. Single-cell omics and heterogeneity of neuroglial cells
16. Imaging neuroglia
