Comprehensive Chemistry and Biology of Coumarins Scaffold

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Comprehensive Chemistry and Biology of Coumarins Scaffold

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  • 製本 Paperback:紙装版/ペーパーバック版/ページ数 400 p.
  • 言語 ENG
  • 商品コード 9780443156502

Full Description

Comprehensive Chemistry and Biology of Coumarins Scaffold covers detailed methods and protocols to synthetize Coumarin derivatives and different applications and future perspectives for these compounds. Coumarin-Based Scaffolds plays an important role in organic, bioorganic, and medicinal chemistry as they act as a bridge between chemistry, life sciences, and biochemical investigations. Coumarin is an important scaffold for designing, generating a wide variety of chemical libraries and drug-like candidates to obtain desired therapeutic and pharmacological properties. Specific functional groups are covered as well as the synthesis of bioactive compounds against specific pathological conditions.

The discovery of new coumarin-based drug candidates during the last decades has been covered to assist the pharmaceutical, bioorganic and medicinal chemists for their further research on coumarin-based molecules.

Contents

1. General Introduction of Coumarin
2. Progress in the Chemistry of Naturally Occurring Coumarins
3. Synthesis and Reactivity of Coumarin Derivatives
4. Recent Progress in the Coumarin-Based Marketed Drugs Development
5. Natural and Synthetic Coumarin Derivatives with Antimicrobial Activities
6. Coumarin as Multi-Targeted Scaffold in Medicinal Chemistry: Potential Anticancer Agents
7. Role of Coumarin and its Privileged Derivatives as Anti-Leishmanial Agents
8. Coumarin: A Privileged Scaffold for the Design and Development of Antidepressant Agents in Medicinal Chemistry
9. Coumarin Skeleton as Anti-inflammatory Agents
10. Medicinal Aspects of Coumarin Based Frameworks as Potential Antioxidant Agents
11. Current Perspectives on Coumarin Classes for Anticoagulant Therapy
12. Coumarin Derivatives: An Emerging Class of Antimutagenic Therapeutic Agents
13. Therapeutic Agents in Alzheimer's Disease: Recent Progress Based on Coumarin Core
14. Coumarin-Based Scaffold as Potential Antidiabetic Agents
15. Recent Developments of Coumarin-Containing Derivatives as Agents for Different Therapies
16. Synthesis, Characterization, and Investigation of Coumarin Based Metal Complexes
17. Therapeutic efficacy and Drug Delivery Route of Coumarin-Based Nanoparticles
18. Understanding the Coumarin Based Polymers
19. Recent Advances in Various Applications of Coumarins: Current Status and Perspectives
20. Coumarins Derivatives: A Brief Discussion on Patents

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