Full Description
A History of Angiogenesis: Discoveries, Research and the Therapeutic Potential presents a recent history of discoveries in the angiogenic field that contribute to the development of the anatomical knowledge of the process, experimental models, and new pharmacological approaches in different angiogenesis-related diseases. This multifaceted book is enriched with deep scientific contents, and each chapter clearly defines historical steps, the emerging role during the years of new morphological findings, molecular pathways, and targets. Focus is also directed on key challenges associated and future directions.
The history of angiogenesis research is an intriguing tool for discovering answers to a wide array of queries arising in the biological and medical world. This comprehensive resource skillfully integrates all the key aspects related to angiogenesis, and will be of immense help to students, researchers, and industry experts who want to explore the last two decades of angiogenesis discoveries and research.
Contents
1 Introduction
2 Angiogenesis before 2000—Cardiovascular system and angiogenesis during the centuries
3 Vasculogenesis, angiogenesis, and new types of vascular growth
4 In vitro and in vivo assays
5 New frontiers in angiogenesis research
6 New frontiers of lymphangiogenesis
7 Early work on the development of inhibitors of angiogenesis as antitumor agents
8 Approved antiangiogenic and proangiogenic drugs in the past two decades: a historical landscape of the therapeutic opportunities
9 Metronomic chemotherapy: more than 20 years of preclinical and clinical evidence
