Radiation Biology : Molecular Foundations and Clinical Applications

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予約

Radiation Biology : Molecular Foundations and Clinical Applications

Rosenstein, Barry S./ Karp, Jerome M.

ウェブストア価格 ¥36,241（本体¥32,947）
Academic Press Inc（2026/09発売）
外貨定価 US$ 165.00
ポイント 329pt

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製本 Paperback:紙装版/ペーパーバック版／ページ数 450 p.
言語 ENG
商品コード 9780443134685

Full Description

Radiation Biology: Molecular Foundations and Clinical Applications is a comprehensive exploration of the effects of radiation on living organisms, delving into the molecular mechanisms underlying cellular responses. This book examines critical topics such as radiation-induced DNA damage, repair processes, and molecular signaling pathways. It provides a detailed look at how cells respond to radiation, addressing cell cycle control, apoptosis, and the effects of radiation on immune system functionality. As a resource for researchers, it bridges the gap between molecular biology and clinical oncology, offering insights into radiation's role in both therapeutic contexts and its broader impact on human biology.

In addition to its focus on molecular responses, the book covers topics like tumor microenvironment and metabolism, the role of epigenetics in radiation biology, and the hallmarks of cancer relevant to radiation therapy. It also provides discussions on chemotherapeutic agents, radiation carcinogenesis, and the complex interplay between radiation and cancer biology. The later sections extend the scope to tissue, organ, and systemic effects of radiation, making it an invaluable reference for professionals in molecular biology, oncology, and related fields striving to push the boundaries of radiation research.

1. Basics of Radiation Physics and Chemistry
2. Radiation-Induced DNA Damages and DNA Repair Processes
3. Molecular Pathways of Cell Death
4. Radiotherapy and Immune Checkpoint Blockade
5. Molecular Signaling in Irradiated Cells
6. Cell-Survival Curves
7. Impact of Cell Cycle Phase, Dose Rate and Kinetic Factors on Radiation Responses
8. The Role of Oxygen in Irradiated Cells
9. The Use of Hypofractionation, Hyperfractionation and Accelerated Treatment in Radiotherapy
10. Angiogenesis, Microenvironment and Metastasis and Radiation Responses
11. Linear Energy Transfer and Relative Biological Effectiveness
12. Radiation Sensitizers
13. Radioprotectors and Radiomitigators
14. Particle Beam Radiotherapy
15. Predictive Assays in Radiotherapy
16. Interaction of Heat and Radiation
17. Classical and Targeted Chemotherapeutic Agents and Interaction with Radiation
18. Radiation Carcinogenesis
19. Hereditary Effects of Radiation
20. In Utero Radiation Effects
21. Radiation Protection Guidelines
22. Normal Tissue and Organ Radiation Responses
23. Whole-Body Radiation Effects
24. Topics in Cancer Biology Relevant to Radiation Oncology