Full Description
Different from other resources, this volume offers a broad appeal to microbiologists, immunologists, and infectious disease specialists on Autoimmune Diseases. The volume covers topics such as skin and alopecia, Kidney, Liver, Paraneoplastic, Resolution of inflammation, Cardiovascular/systemic inflammation and atherosclerosis, Gut, Regulatory lymphocytes T, B, other and Rheumatic Disease. The volume is written by internationally renowned authors who are authorities in their respective fields.
Contents
B cell development and repertoire sel: B cell central tolerance: controlling self-reactive B cells in the bone marrow.- B cell tolerance.- B cell trafficking.- B1 cells.- BCR signaling.- CS and SHM.- MZB cells.- Plasma Cells.- Regulatory B cells.- Repertoire selection.- TFH help.- Cardiovascular/systemic inflammation: Atherosclerosis and cytokines.-Autoantibodies and atherosclerosis.- Autoantibodies to endothelial cells.- Autoimmune disease and premature atherosclerosis.- Autoimmune heart disease animal models.- Autoimmune myocarditis and pericarditis.- Cell adhesion molecules.- Dendritic cells and atherosclerosis.- Endothelial cells and inflammation.- Immune mediated mechanisms of the metabolic syndrome.- Lymphocytes in Atherosclerosis.- Macrophages, Oxidative stress and Atherosclerosis.- Mechanisms of endothelial activation.- Neutrophils in endothelial damage.- Platelets, atherosclerosis and immunity.- Viral myocarditis.- Gut: Celiac disease.- Overview of theGut microbiome.- Overview on IBD.- Overview on mucosal immunity.- Liver: Adaptive immune cells in the liver.- AIH: clinical + systemic manifestations and treatment.- AIH: Pathogenesis, association with other syndromes.- Animal models of AIH.- Animal models of hepatitis B and C.- Gestational Alloimmune Liver Disease.- Immune response during acute and chronic Hepatitis B.- Immune response during acute and chronic Hepatitis C.- Immunosuppression in clinical liver transplantation.- Innate immune cells in the liver.- KC and tolerance.- Liver transplantation tolerance in animal models.- Liver vasculature and microvasculature.- LSEC and tolerance.- PBC genetics.- PBC: clinical + systemic manifestations and treatment.- Primary T Cell activation in the liver.- PSC: clinical + systemic manifestations and treatment.- The hepatic lymphatic system.- Transplantation for auto immune diseases.- Transplantation for chronic viral hepatitis.- Tregs in the liver.- Ultrastructure of the liver sinusoid.- Lymphocytes activation T, B, NK: B7/CD28 family.- Bcl-2 family.- CD40.- CD5.- Chemokines.- CTLA4-Ig.- Cytotoxic T cells.- FcRIIb.- GTPases.- IL-21.- Interleukin 6.- LAT.- mTOR.- NFAT.- NFkB.- NK cell activation.- PI3K.- PKCtheta.- PTPN22.- Rho/Rac GTPases.- SHIP.- T cell memory.- Paraneoplastic: Cancer and dermatomyositis.- Cancer and Fever.- Cancer and joint pain.- Cancer and nephrotic syndrome.- Cancer and neuropathies.- Cancer and the CNS.- Cancer and thrombosis.- Cancer therapies and autoimmunity.- Paraneoplastic Syndromes, an overview.- Tumor Infiltrating T cells.- Tumor Macrophages.- Resolution of Inflammation: Anti-oxidants.- CD5.- CTLA 4.- EICOSANOIDS (prostaglandins, leucotrienes, and related compounds).- Fas/fas ligand.- Fibrosis.- Nitric oxide.- Polymorphonuclear Leucocytes (PMN)/neutrophils.- Resolution of Inflammation.- TGFbeta.- Kidney: Anti-GBM GN.- Autoimmune disease.- Autoimmune Kidney Disease and Pregnancy.- Autoimmunity and Inflammation in Diabetic Nephropathy.- Complement regulation in the Kidney.- IgA Nephropathy.- Immune System and the Kidney.- Impact of Recurrent Autoimmune Diseases in Renal Transplant Outcomes.- Indications for Biopsy in Autoimmune GN.- Pathogenesis of Lupus Nephritis and New Approaches to Treatment.- Proteinuric Kidney Diseases: Importance of Blood Pressure Control.- Scleroderma Renal Crisis.- Spectrum of Minimal Change Disease to Focal Segmental Glomerulosclerosis.- Translational aspects of MN.- TTP and the Kidney.- Vasculitits and the Kidney (ANCA, etc).- Regulatory lymphocytes T, B, other: Regulatory B cells.- Tregs: Regulatory T cells.- Rheumatic Disease: APLS- Mechanism of thrombosis.- APLS- treatment.- APLS-Clinical Manifestations.- Autoinflammatory Syndromes.- Complement in rheumatic diseases.- Diagnosis and Treatment of Lupus Nephritis.- Environment and autoimmunity.- Epigenetics in autoimmunity.- Immunodeficiency in Autoimmune diseases.- Juvenile diseases: Arthritis treatment in children (incl. pathogenesis, presentation & treatment).- Juvenile diseases: Genetics of JIA.- Juvenile diseases: Juvenile arthritis syndromes.- Juvenile diseases: Kawasaki syndrome.- Juvenile diseases: SLE-children.- microRNA in autoimmunity.- Myositis pathogenesis.- Myositis-Dermatomyositis, Polymyositis, inclusion body myositis, and autoantibodies.- Myositis: Juvenile myositis.- Nephritogenic autoantibodies in SLE.- RA- clinical features.- RA- extraarticular manifestations.- RA-animal models.- RA-autoantibodies.- RA-genetics.- RA-treatment.- RA: Biologics in the treatment of RA.- RA: Small molecules.- Raynauds phenomenon.- Sarcoidosis.- Scleroderma-genetics.- Scleroderma: Pathogenesis and Clinical Manifestations.- Sjogren's syndrome.- SLE - Clinical Trials in SLE.- SLE - Discoid SLE.- SLE - Novel targets in SLE Essay.- SLE-animal models.- SLE-autoantibodies.- SLE-clinical features and diagnosis.- SLE-gender and hormonal influences.- SLE-genetics.- SLE-pathogenesis.- SLE-pregnancy.- SLE-skin.- SLE-treatment.- SLE: Congenital heart block and neonatal lupus.- SLE: Mixed connective tissue disease (MCTD).- Spondyloarthritis: Ankylosing Spondylitis.- Spondyloarthritis: Psoriatic arthritis.- Spondyloarthritis: Reactive Arthritis.- Treatment (current and upcoming) of scleroderma.- Vasculitis: Bechets.- Vasculitis: Churg-Strauss syndrome.-Vasculitis: Cutaneous vasculitis (hypersensitivity vasculitis).- Vasculitis: Giant cell arteritis.-Vasculitis: Henoch-Schonlein purpura.- Vasculitis: Microscopic polyangiitis.- Vasculitis: Polyarteritis nodosa.- Vasculitis: Polymyalgia rheumatica.- Vasculitis: Primary CNS vasculitis.-Vasculitis: Wegenerâ??s granulomatosis.- Skin and Alopecia: Alopecia areata.- Autoimmune Blistering Diseases.- Blistering diseases: Bullous Pemphigoid.- Blistering diseases: Mucous Membrane Pemphigoid.- Blistering diseases: Linear IgA disease (LAD).- Blistering diseases: Pemphigus.- Dermatomyositis.- Erythema nodosum.- HairLoss In Lupus Erythematosus.- Inflammatory - SLE - Skin.- Inflammatory: Dermatomyositis - skin.- Inflammatory: Discoid lupus.- Inflammatory: psoriasis cutaneous.- Lichen Planopilaris.- Lichen planus.- Neutrophilic dermatoses: Sweets syndrome.- Neutrophilic dermatoses: Leukocytoclastic vasculitis.- Neutrophilic dermatoses: Pyoderma gangrenosum.- Scleroderma like conditions.- Skin and Alopecia.- Vitiligo.
