Full Description
Alternative Splicing in the Postgenomic Era is the first book that is solely dedicated to the topic of alternative splicing. The book contains chapters by experts in the field that cover nearly all aspects of alternative splicing. The purpose of this book is to provide a single, authoritative source of information on alternative splicing that is accessible to researchers in diverse fields. The book contains information that will familiarize readers that have not previously encountered alternative splicing, but also contains sufficient depth to provide new information to experts in the field.
Contents
Nuclear Organization and Splicing Control.- Spliceosome Assembly and Composition.- Relating Alternative Splicing to Proteome Complexity and Genome Evolution.- Complex Alternative Splicing.- Technologies for the Global Discovery and Analysis of Alternative Splicing.- Searching for Splicing Motifs.- SR Proteins and Related Factors in Alternative Splicing.- hnRNP Proteins and Splicing Control.- Functional and Mechanistic Insights From Genome-Wide Studies of Splicing Regulation in the Brain.- Regulation of Alternative Splicing by Signal Transduction Pathways.- Coupling Transcription and Alternative Splicing.- The Coupling of Alternative Splicing and Nonsense-Mediated mRNA Decay.- Alternative Splicing in Disease.
